APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
| Application |
Recommended Dilution |
| 1 - 2 μg/mL |
| 5 μg/mL |
| Assay dependent |
Not tested in other applications.
Calculated MW
Positive Control
Hep G2 Cell Slide(GTX25530) , HepG2 Cell Lysate(GTX27900)
Product Note
At least two isoforms of CXCR3 are known to exist; this antibody will detect both isoforms.
PROPERTIES
Form
Liquid
Buffer
PBS
Preservative
0.02% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
CXCR3 antibody was raised against a 19 amino acid peptide near the carboxy terminus of human CXCR3 .The immunogen is located within the last 50 amino acids of CXCR3.
Purification
Purified by antigen-affinity chromatography
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
C-X-C motif chemokine receptor 3 , CD182 , CD183 , CKR-L2 , CMKAR3 , GPR9 , IP10-R , Mig-R , MigR
Background
This gene encodes a G protein-coupled receptor with selectivity for three chemokines, termed CXCL9/Mig (monokine induced by interferon-g), CXCL10/IP10 (interferon-g-inducible 10 kDa protein) and CXCL11/I-TAC (interferon-inducible T cell a-chemoattractant). Binding of chemokines to this protein induces cellular responses that are involved in leukocyte traffic, most notably integrin activation, cytoskeletal changes and chemotactic migration. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. One of the isoforms (CXCR3-B) shows high affinity binding to chemokine, CXCL4/PF4 (PMID:12782716). [provided by RefSeq, Jun 2011]
Database
Research Area
DATA IMAGES
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GTX31566 ICC/IF Image
ICC/IF analysis of HepG2 cells using GTX31566 CXCR3 antibody.
Working concentration : 20 μg/ml
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GTX31566 ICC/IF Image
ICC/IF analysis of HepG2 cells using GTX31566 CXCR3 antibody.
Working concentration : 5 μg/ml
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GTX31566 WB Image
WB analysis of HepG2 cell lysate using GTX31566 CXCR3 antibody.
Working concentration : (A) 1 and (B) 2 μg/ml
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REFERENCE
There are currently no references for CXCR3 antibody (GTX31566). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for CXCR3 antibody (GTX31566). Be the first to share your experience with this product.
