GeneTex
United States (US)

CXCR3 antibody

GTX31566_2751_WB_20180221_18121410_470.jpg
GTX31566_211_ICC-IF_20180221_18121410_413.jpg
GTX31566_212_ICC-IF_20180221_18121410_668.jpg

Cat No. GTX31566

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, ICC/IF, ELISA
Reactivity Human, Mouse, Rat
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1 - 2 μg/mL
ICC/IF 5 μg/mL
ELISA Assay dependent
Not tested in other applications.

Calculated MW

41 kDa. ( Note )

Positive Control

Hep G2 Cell Slide(GTX25530) , HepG2 Cell Lysate(GTX27900)

Specificity/Sensitivity

At least two isoforms of CXCR3 are known to exist; this antibody will detect both isoforms.
PROPERTIES

Form

Liquid

Buffer

PBS with 0.02% sodium azide.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

CXCR3 antibody was raised against a 19 amino acid peptide near the carboxy terminus of human CXCR3 .The immunogen is located within the last 50 amino acids of CXCR3.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

C-X-C Motif Chemokine Receptor 3,Cd182,Cd183,Ckr-L2,Cmkar3,Gpr9,Ip10-R,Mig-R,Migr,Cxcr3

Background

This gene encodes a G protein-coupled receptor with selectivity for three chemokines, termed CXCL9/Mig (monokine induced by interferon-g), CXCL10/IP10 (interferon-g-inducible 10 kDa protein) and CXCL11/I-TAC (interferon-inducible T cell a-chemoattractant). Binding of chemokines to this protein induces cellular responses that are involved in leukocyte traffic, most notably integrin activation, cytoskeletal changes and chemotactic migration. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. One of the isoforms (CXCR3-B) shows high affinity binding to chemokine, CXCL4/PF4 (PMID:12782716). [provided by RefSeq, Jun 2011]

Database

Research Area

DATA IMAGES
GTX31566_2751_WB_20180221_18121410_470.jpg

GTX31566 WB Image

WB analysis of HepG2 cell lysate using GTX31566 CXCR3 antibody.
Working concentration : (A) 1 and (B) 2 μg/ml

GTX31566_211_ICC-IF_20180221_18121410_413.jpg

GTX31566 ICC/IF Image

ICC/IF analysis of HepG2 cells using GTX31566 CXCR3 antibody.
Working concentration : 5 μg/ml

GTX31566_212_ICC-IF_20180221_18121410_668.jpg

GTX31566 ICC/IF Image

ICC/IF analysis of HepG2 cells using GTX31566 CXCR3 antibody.
Working concentration : 20 μg/ml

Package List Price ($)
$ 339