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CXCR4 antibody [12G5] (PE-Cy5)

Cat No. GTX00549-09

Host

Mouse

Clonality

Monoclonal

Clone Name

12G5

Isotype

IgG2a

Application

FACS

Reactivity

Human, Primate
Package
100 test ($329)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
FACS 4 μl reagent / 100 μl of whole blood or 10⁶ cells in a suspension
Not tested in other applications.

Calculated MW

40 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 15mM sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE. Protect from light.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

CP-MAC-infected Sup-T1 cells

Purification

Purified by size-exclusion chromatography

Conjugation

Phycoerythrin-Cyanine5 (PE-Cy5)

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption. Cy and CyDye are trademarks of GE Healthcare.

TARGET

Synonyms

CD184,CXC motif chemokine receptor 4,CXCR4,D2S201E,FB22,HM89,HSY3RR,LAP3,LCR1,LESTR,NPY3R,NPYR,NPYRL,NPYY3R,WHIM,WHIMS,C-X-C motif chemokine receptor 4

Cellular Localization

Cell membrane,Cell junction,Early endosome,Late endosome,Lysosome

Background

This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]

Database

Research Area

REFERENCE

There are currently no references for CXCR4 antibody [12G5] (PE-Cy5) (GTX00549-09). Be the first to share your publications with this product.

REVIEW

There are currently no reviews for CXCR4 antibody [12G5] (PE-Cy5) (GTX00549-09). Be the first to share your experience with this product.