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CXCR4 antibody [HL2734]

Recombinant antibody
Anti-CXCR4 antibody [HL2734] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX639562
Anti-CXCR4 antibody [HL2734] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX639562

Cat. No. GTX639562

Host

 Rabbit

Clonality

 Monoclonal

Clone Name

 HL2734

Isotype

 IgG

Application

 ICC/IF

Reactivity

 Human
Package
100 μl ($419),
25 μl ($169)
See all CXCR4 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
ICC/IF 1:100-1:1000
Not tested in other applications.

Product Note

This antibody was raised against human CXCR4 Extracellular domain.

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

No preservative

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

carrier-protein conjugated synthetic peptide encompassing a sequence within the Extracellular domain of human CXCR4. The exact sequence is proprietary.

Purification

Affinity purified by Protein A.

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

C-X-C motif chemokine receptor 4 , CD184 , D2S201E , FB22 , HM89 , HSY3RR , LAP-3 , LAP3 , LCR1 , LESTR , NPY3R , NPYR , NPYRL , NPYY3R , WHIM , WHIMS

Cellular Localization

Cell membrane,Cell junction,Early endosome,Lysosome

Background

This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-CXCR4 antibody [HL2734] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX639562

GTX639562 ICC/IF Image

CXCR4 antibody [HL2734] detects CXCR4 protein by immunofluorescent analysis.
Sample: Mock and transfected 293T cells were fixed in ice-cold MeOH for 5 min.
Green: CXCR4 stained by CXCR4 antibody [HL2734] (GTX639562) diluted at 1:500.
Blue: Fluoroshield with DAPI (GTX30920).

Anti-CXCR4 antibody [HL2734] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX639562

GTX639562 ICC/IF Image

CXCR4 antibody [HL2734] detects CXCR4 protein by immunofluorescent analysis.
Sample: Jurkat cells were fixed in 4% paraformaldehyde at RT for 15 min.
Green: CXCR4 stained by CXCR4 antibody [HL2734] (GTX639562) diluted at 1:500.
Blue: Fluoroshield with DAPI (GTX30920).

REFERENCE

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REVIEW

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Package List Price ($)
$ 419
$ 169
Custom Conjugations