GeneTex
United States (US)

CXCR4 (phospho Ser339) antibody

Anti-CXCR4 (phospho Ser339) antibody used in Western Blot (WB). GTX32281

Cat No. GTX32281

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB
Reactivity Human, Mouse, Rat
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500 - 1:1000
Not tested in other applications.

Calculated MW

40 kDa. ( Note )
PROPERTIES

Form

Liquid

Buffer

0.42% Potassium phosphate, 0.87% Sodium chloride pH 7.3, 30% glycerol, 0.01% sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20º C or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of CXCR4. The exact sequence is proprietary.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

C-X-C Motif Chemokine Receptor 4,Cd184,D2S201E,Fb22,Hm89,Hsy3Rr,Lap-3,Lap3,Lcr1,Lestr,Npy3R,Npyr,Npyrl,Npyy3R,Whim,Whims,Cxcr4

Cellular Localization

Cell junction,Cell membrane,Early endosome,Late endosome,Lysosome

Background

This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES
Anti-CXCR4 (phospho Ser339) antibody used in Western Blot (WB). GTX32281

GTX32281 WB Image

WB analysis of colchicine-treated HEK293T (A), HL60 (B), Jurkat (C), mouse spleen (D), rat spleen (E) whole cell lysates using GTX32281 CXCR4 (phospho Ser339) antibody.

REFERENCE