PBS with 0.02% sodium azide
Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.
0.5 mg/ml (Please refer to the vial label for the specific concentration.)
Synthetic peptide, corresponding to amino acids 319-338 of Human CXCR6.
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
C-X-C Motif Chemokine Receptor 6,Bonzo,Cd186,Strl33,Tymstr,Cxcr6
Integral membrane protein
Human immunodeficiency virus (HIV) and simian immunodeficiency virus (SIV) require co-receptors, in addition to CD4, to infect target cells. Some G-protein coupled receptors including CCR5, CXCR4, CCR3, and CCR2b in the chemokine receptor family have been identified as HIV co-receptors. An orphan G-protein coupled receptor was recently cloned and designated Bonzo, STRL33 and TYMSTR, and identified as HIV and SIV co-receptor (1-4). Bonzo/STRL33 is used by SIV, HIV-2 and HIV-1. The messenger RNA of Bonzo/STRL33 is expressed in lymphoid tissues and activated peripheral blood lymphocytes.