CXCR7 antibody [C1C2], Internal
Cat. No. GTX100027
Cat. No. GTX100027
This CXCR7 antibody [C1C2], Internal (GTX100027) is a rabbit polyclonal antibody validated for detection of CXCR7 by WB, ICC/IF, IHC-P, IHC-Fr, FCM, IP, and ELISA. Reactivity has been shown in Human, Mouse, and Rat. This product is cited in 28 published studies. Knockout/knockdown validation supports antibody specificity.
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HostRabbit
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ClonalityPolyclonal
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IsotypeIgG
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ApplicationsWB ICC/IF IHC-P IHC-Fr FCM IP ELISA
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ReactivityHuman, Mouse, Rat
Summary
CXCR7 antibody recognizes C-X-C chemokine receptor type 7 (CXCR7), now known as atypical chemokine receptor 3 (ACKR3). This chemokine receptor (with a predicted molecular weight of 41 kDa) binds the chemokines CXCL11 and CXCL12 and other non-chemokine ligands such as adrenomedullin and MIF. ACKR3 plays important roles in cardiovascular and neuronal development and acts as a scavenger receptor to regulate both chemokine- and opioid peptide-dependent signaling.