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CXCR7 antibody

Anti-CXCR7 antibody used in IHC (Paraffin sections) (IHC-P). GTX82935
Anti-CXCR7 antibody used in Western Blot (WB). GTX82935
Anti-CXCR7 antibody used in IHC (Paraffin sections) (IHC-P). GTX82935

Cat. No. GTX82935

Reference 2

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P, IP, ELISA, IHC

Reactivity

 Human, Mouse, Rat, Monkey, Baboon
Package
50 μg ($399)
See all CXCR7 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500
IHC-P Assay dependent
IP 1:250
ELISA Assay dependent
IHC 1:250
Not tested in other applications.

Calculated MW

41 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

Tris/Glycine, 0.5% BSA, 30% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.68 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Synthetic peptide corresponding to unique amino acid sequence on human CXCR7 protein.

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

RRID

AB_809721

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

atypical chemokine receptor 3 , CMKOR1 , CXC-R7 , CXCR-7 , CXCR7 , GPR159 , RDC-1 , RDC1

Cellular Localization

Cell membrane; Multi-pass membrane protein

Background

This gene encodes a member of the G-protein coupled receptor family. Although this protein was earlier thought to be a receptor for vasoactive intestinal peptide (VIP), it is now considered to be an orphan receptor, in that its endogenous ligand has not been identified. The protein is also a coreceptor for human immunodeficiency viruses (HIV). Translocations involving this gene and HMGA2 on chromosome 12 have been observed in lipomas. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-CXCR7 antibody used in IHC (Paraffin sections) (IHC-P). GTX82935

GTX82935 IHC-P Image

IHC-P analysis of baboon small intestine tissue using GTX82935 CXCR7 antibody.
Dilution : 1:100

Anti-CXCR7 antibody used in Western Blot (WB). GTX82935

GTX82935 WB Image

WB analysis of mouse cerebellum tissue lysate using GTX82935 CXCR7 antibody.
Dilution : 1:250

Anti-CXCR7 antibody used in IHC (Paraffin sections) (IHC-P). GTX82935

GTX82935 IHC-P Image

IHC-P analysis of rat small intestine tissue using GTX82935 CXCR7 antibody.
Dilution : 1:100

REFERENCE

Application Reference

Wu YC et al. Oncogene 2015; (Epub) CXCR7 mediates TGFβ1-promoted EMT and tumor-initiating features in lung cancer.
Application : IHC
Reactivity : Human
McGinn OJ et al. J Cell Sci 2012; 125 (Pt 22) : 5467-78 CXCL12 receptor preference, signal transduction, biological response and the expression of 5T4 oncofoetal glycoprotein.
Application : WB
Reactivity : Mouse
Submit a Reference

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Package List Price ($)
$ 399