GeneTex
United States (US)

CYP11A1 antibody

GTX53941_20180530_ICCIF_18121410_915.jpg
GTX53941_20180530_WB_18121410_722.jpg

Cat No. GTX53941

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, ICC/IF
Reactivity Human, Rat
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500 - 1:2000
ICC/IF 1:50 - 1:200
Not tested in other applications.

Calculated MW

60 kDa. ( Note )
PROPERTIES

Form

Liquid

Buffer

PBS pH7.3, 0.02% sodium azide, 50% glycerol.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Recombinant funsion protein containing a sequence corresponding to amino acids 40-320 of human CYP11A1 (NP_000772.2).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

CYP11A Antibody , CYPXIA1 Antibody , P450SCC Antibody

Background

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane and catalyzes the conversion of cholesterol to pregnenolone, the first and rate-limiting step in the synthesis of the steroid hormones. Two transcript variants encoding different isoforms have been found for this gene. The cellular location of the smaller isoform is unclear since it lacks the mitochondrial-targeting transit peptide. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES
GTX53941_20180530_ICCIF_18121410_915.jpg

GTX53941 ICC/IF Image

ICC/IF analysis of MCF-7 cell using GTX53941 CYP11A1 antibody.
Blue : DAPI

GTX53941_20180530_WB_18121410_722.jpg

GTX53941 WB Image

WB analysis of various samples using GTX53941 CYP11A1 antibody.
Dilution : 1:2000
Loading : 25μg per lane

Package List Price ($)
$ 319