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CYP17A1 antibody [6E1-H9-F6]

Anti-CYP17A1 antibody [6E1-H9-F6] used in Western Blot (WB). GTX49265

Cat No. GTX49265

Host

Mouse

Clonality

Monoclonal

Clone Name

6E1-H9-F6

Isotype

IgG2b

Application

WB

Reactivity

Human
Package
100 μg ($319)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB Assay dependent
Not tested in other applications.

Calculated MW

60 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

Ascites

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Purified recombinant human CYP17A1 protein fragments expressed in E.coli.

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

Cytochrome P450 Family 17 Subfamily A Member 1 , Cpt7 , Cyp17 , P450C17 , S17Ah , Cyp17A1

Cellular Localization

Membrane.

Background

This gene encodes a member of the cytochrome P450 superfamily of enzymes.The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol,steroids and other lipids.This protein localizes to the endoplasmic reticulum.It has both 17alpha-hydroxylase and 17,20-lyase activities and is a key enzyme in the steroidogenic pathway that produces progestins,mineralocorticoids,glucocorticoids,androgens,and estrogens.Mutations in this gene are associated with isolated steroid-17 alpha-hydroxylase deficiency,17-alpha-hydroxylase/17,20-lyase deficiency,pseudohermaphroditism,and adrenal hyperplasia.[provided by RefSeq,Jul 2008]

Database

Research Area

DATA IMAGES

Anti-CYP17A1 antibody [6E1-H9-F6] used in Western Blot (WB). GTX49265

GTX49265 WB Image

WB analysis of A549, HepG2 and HeLa lysates using Cytochrome P450 17A1 antibody at a dilution of 1:1,000.

REFERENCE

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REVIEW

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