APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
| Application |
Recommended Dilution |
| 1:1000 |
| 1:10-1:50 |
Not tested in other applications.
Calculated MW
Predict Reactivity
Monkey(>80% identity)
PROPERTIES
Form
Liquid
Buffer
PBS
Preservative
0.09% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
Batch dependent (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
KLH conjugated synthetic peptide between 377-405 amino acids from the C-terminal region of human CYP1A1.
Purification
Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
cytochrome P450 family 1 subfamily A member 1 , AHH , AHRR , CP11 , CYP1 , CYPIA1 , P1-450 , P450-C , P450DX
Cellular Localization
Endoplasmic reticulum membrane,Mitochondrion inner membrane,Cytoplasm
Background
This gene, CYP1A1, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown; however, it is able to metabolize some PAHs to carcinogenic intermediates. The gene has been associated with lung cancer risk. A related family member, CYP1A2, is located approximately 25 kb away from CYP1A1 on chromosome 15. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jan 2016]
Database
Research Area
DATA IMAGES
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GTX81232 WB Image
WB analysis of mouse lung tissue lysate (35ug/lane) using GTX81232 CYP1A1 antibody, C-term.
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GTX81232 WB Image
WB analysis of K562 cell lysate (35ug/lane) using GTX81232 CYP1A1 antibody, C-term.
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GTX81232 IHC-P Image
IHC-P analysis of human lung carcinoma using GTX81232 CYP1A1 antibody, C-term.
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REFERENCE
There are currently no references for CYP1A1 antibody, C-term (GTX81232). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for CYP1A1 antibody, C-term (GTX81232). Be the first to share your experience with this product.
