*Optimal dilutions/concentrations should be determined by the researcher.
Not tested in other applications.
293T , A431 , H1299 , HeLaS3 , HepG2 , Molt-4 , Raji
Rat, Pig(>80% identity)
0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Recombinant protein encompassing a sequence within the center region of human CYP24A1. The exact sequence is proprietary.
Purified by antigen-affinity chromatography.
For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
CP24 antibody, CYP24 antibody, MGC126273 antibody, MGC126274 antibody, P450-CC24 antibody, CYP24A1 antibody, 24-OHase antibody, cytochrome P450, subfamily XXIV (vitamin D 24-hydroxylase) antibody, cytochrome P450-CC24 antibody, vitamin D(3) 24-hydroxylase antibody, cytochrome P450 24A1 antibody, vitamin D 24-hydroxylase antibody, exo-mitochondrial protein antibody, 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial antibody, 1,25-@dihydroxyvitamin D3 24-hydroxylase antibody, cytochrome P450, family 24, subfamily A, polypeptide 1 antibody
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This mitochondrial protein initiates the degradation of 1,25-dihydroxyvitamin D3, the physiologically active form of vitamin D3, by hydroxylation of the side chain. In regulating the level of vitamin D3, this enzyme plays a role in calcium homeostasis and the vitamin D endocrine system. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]