GeneTex
United States (US)

CYP2B6 antibody

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Cat No. GTX64899

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, IHC-P
Reactivity Human, Mouse
See all CYP2B6 products
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500 - 1:1000
IHC-P Assay dependent
Not tested in other applications.

Calculated MW

56 kDa. ( Note )
PROPERTIES

Form

Liquid

Buffer

PBS pH7.3, 0.02% sodium azide, 50% glycerol.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Recombinant funsion protein containing a sequence corresponding to amino acids 160-340 of human CYP2B6 (NP_000758.1).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

CYP2B Antibody , CYPIIB6 Antibody , CYP2B7 Antibody , CPB6 Antibody , P450 Antibody , EFVM Antibody , CYP2B7P Antibody , IIB1 Antibody

Background

This gene, CYP2B6, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by phenobarbital. The enzyme is known to metabolize some xenobiotics, such as the anti-cancer drugs cyclophosphamide and ifosphamide. Transcript variants for this gene have been described; however, it has not been resolved whether these transcripts are in fact produced by this gene or by a closely related pseudogene, CYP2B7. Both the gene and the pseudogene are located in the middle of a CYP2A pseudogene found in a large cluster of cytochrome P450 genes from the CYP2A, CYP2B and CYP2F subfamilies on chromosome 19q. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES
GTX64899_20180530_WB_18121411_775.jpg

GTX64899 WB Image

WB analysis of various samples using GTX64899 CYP2B6 antibody.The signal was developed with ECL plus-Enhanced.
Dilution : 1:1000
Loading : 25μg per lane
GTX64899_20180530_IHC-P_5_18121411_354.jpg

GTX64899 IHC-P Image

IHC-P analysis of human stomach tissue using GTX64899 CYP2B6 antibody.
Dilution : 1:100
GTX64899_20180530_IHC-P_7_18121411_723.jpg

GTX64899 IHC-P Image

IHC-P analysis of mouse kidney tissue using GTX64899 CYP2B6 antibody.
Dilution : 1:100
GTX64899_20180530_IHC-P_9_18121411_530.jpg

GTX64899 IHC-P Image

IHC-P analysis of mouse lung tissue using GTX64899 CYP2B6 antibody.
Dilution : 1:100
GTX64899_20180530_IHC-P_4_18121411_516.jpg

GTX64899 IHC-P Image

IHC-P analysis of human lung tissue using GTX64899 CYP2B6 antibody.
Dilution : 1:100
GTX64899_20180530_IHC-P_6_18121411_453.jpg

GTX64899 IHC-P Image

IHC-P analysis of mouse brain tissue using GTX64899 CYP2B6 antibody.
Dilution : 1:100
GTX64899_20180530_IHC-P_3_18121411_384.jpg

GTX64899 IHC-P Image

IHC-P analysis of human gastric cancer tissue using GTX64899 CYP2B6 antibody.
Dilution : 1:100
GTX64899_20180530_IHC-P_18121411_812.jpg

GTX64899 IHC-P Image

IHC-P analysis of human breast cancer tissue using GTX64899 CYP2B6 antibody.
Dilution : 1:100
GTX64899_20180530_IHC-P_8_18121411_416.jpg

GTX64899 IHC-P Image

IHC-P analysis of mouse liver tissue using GTX64899 CYP2B6 antibody.
Dilution : 1:100
GTX64899_20180530_IHC-P_1_18121411_239.jpg

GTX64899 IHC-P Image

IHC-P analysis of human colon carcinoma tissue using GTX64899 CYP2B6 antibody.
Dilution : 1:100
GTX64899_20180530_IHC-P_2_18121411_154.jpg

GTX64899 IHC-P Image

IHC-P analysis of human colon tissue using GTX64899 CYP2B6 antibody.
Dilution : 1:100
Package List Price ($)
$ 319