APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
Application |
Recommended Dilution |
0.2-2.5 ug/ml |
Not tested in other applications.
Calculated MW
Positive Control
human B lymphoblast , human fetal muscle , human placenta
PROPERTIES
Form
Liquid
Buffer
PBS, 2% Sucrose
Preservative
0.09% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
0.5-1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
A synthetic peptide corresponding to an Internal region of Human CYP2C19
Purification
Affinity Purified
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
cytochrome P450 family 2 subfamily C member 19 , CPCJ , CYP2C , CYPIIC17 , CYPIIC19 , P450C2C , P450IIC19
Background
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is known to metabolize many xenobiotics, including the anticonvulsive drug mephenytoin, omeprazole, diazepam and some barbiturates. Polymorphism within this gene is associated with variable ability to metabolize mephenytoin, known as the poor metabolizer and extensive metabolizer phenotypes. The gene is located within a cluster of cytochrome P450 genes on chromosome 10q24. [provided by RefSeq, Jul 2008]
Database
Research Area
DATA IMAGES
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GTX47113 WB Image
WB analysis of human fetal muscle tissue using GTX47113 CYP2C19 antibody at 1.0μg/ml.
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GTX47113 WB Image
WB analysis of human B lymphoblast cells using GTX47113 CYP2C19 antibody at 1.0μg/ml.
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GTX47113 WB Image
WB analysis of human placenta tissue using GTX47113 CYP2C19 antibody at 0.2-1μg/ml.
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REFERENCE
There are currently no references for CYP2C19 antibody, Internal (GTX47113). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for CYP2C19 antibody, Internal (GTX47113). Be the first to share your experience with this product.