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CYP2C19 antibody, Internal

Anti-CYP2C19 antibody, Internal used in Western Blot (WB). GTX81761
Anti-CYP2C19 antibody, Internal used in IHC (Paraffin sections) (IHC-P). GTX81761
Anti-CYP2C19 antibody, Internal used in Western Blot (WB). GTX81761

Cat. No. GTX81761

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P

Reactivity

 Human
Package
400 μl ($399)
See all CYP2C19 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:1000
IHC-P 1:10-1:50
Not tested in other applications.

Calculated MW

56 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.09% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

KLH conjugated synthetic peptide between 257-285 amino acids from the Central region of human CYP2C19.

Purification

Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

cytochrome P450 family 2 subfamily C member 19 , CPCJ , CYP2C , CYPIIC17 , CYPIIC19 , P450C2C , P450IIC19

Background

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is known to metabolize many xenobiotics, including the anticonvulsive drug mephenytoin, omeprazole, diazepam and some barbiturates. Polymorphism within this gene is associated with variable ability to metabolize mephenytoin, known as the poor metabolizer and extensive metabolizer phenotypes. The gene is located within a cluster of cytochrome P450 genes on chromosome 10q24. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-CYP2C19 antibody, Internal used in Western Blot (WB). GTX81761

GTX81761 WB Image

WB analysis of Jurkat cell lysate (35ug/lane) using GTX81761 CYP2C19 antibody, Internal.

Anti-CYP2C19 antibody, Internal used in IHC (Paraffin sections) (IHC-P). GTX81761

GTX81761 IHC-P Image

IHC-P analysis of human liver tissue using GTX81761 CYP2C19 antibody, Internal.

Anti-CYP2C19 antibody, Internal used in Western Blot (WB). GTX81761

GTX81761 WB Image

WB analysis of human liver lysate using GTX81761 CYP2C19 antibody, Internal.
Loading : 20 μg per lane
Dilution : 1:2000

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399