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CYP3A4 antibody [JA11-33]

Recombinant antibody
Anti-CYP3A4 antibody [JA11-33] used in IHC (Paraffin sections) (IHC-P). GTX01025

Cat No. GTX01025

Host

Rabbit

Clonality

Monoclonal

Clone Name

JA11-33

Isotype

IgG

Application

IHC-P

Reactivity

Human
Package
100 μl ($369)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
IHC-P 1:50-1:200
Not tested in other applications.

Calculated MW

57 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

1x TBS (pH7.4), 1% BSA, 40% glycerol, 0.05% sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant protein

Purification

Protein A purified

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

cytochrome P450 family 3 subfamily A member 4,CP33,CP34,CYP3A,CYP3A3,CYP3A4,CYPIIIA3,CYPIIIA4,HLP,NF25,P450C3,P450PCN1,Cytochrome P450 3A4

Cellular Localization

Endoplasmic reticulum membrane,Microsome membrane

Background

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases that catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by glucocorticoids and some pharmacological agents. This enzyme is involved in the metabolism of approximately half the drugs in use today, including acetaminophen, codeine, cyclosporin A, diazepam and erythromycin. The enzyme also metabolizes some steroids and carcinogens. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. Previously another CYP3A gene, CYP3A3, was thought to exist; however, it is now thought that this sequence represents a transcript variant of CYP3A4. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Feb 2011]

Database

Research Area

DATA IMAGES

Anti-CYP3A4 antibody [JA11-33] used in IHC (Paraffin sections) (IHC-P). GTX01025

GTX01025 IHC-P Image

IHC-P analysis of human liver tissue section using GTX01025 CYP3A4 antibody [JA11-33].

REFERENCE

There are currently no references for CYP3A4 antibody [JA11-33] (GTX01025). Be the first to share your publications with this product.

REVIEW

There are currently no reviews for CYP3A4 antibody [JA11-33] (GTX01025). Be the first to share your experience with this product.
Package List Price ($)
$ 369