GeneTex

  • Country / Location Selection

United States (US)

CYP7B1 antibody

Anti-CYP7B1 antibody used in IHC (Paraffin sections) (IHC-P). GTX04543
Anti-CYP7B1 antibody used in IHC (Paraffin sections) (IHC-P). GTX04543
Anti-CYP7B1 antibody used in Western Blot (WB). GTX04543

Cat. No. GTX04543

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P

Reactivity

 Human
Package
100 μl ($399)
See all CYP7B1 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500-1:1000
IHC-P 1:50-1:200
Not tested in other applications.

Calculated MW

58 kDa. ( Note )

Predict Reactivity

Rabbit, Sheep, Bovine, Dog, Pig, Horse(>80% identity)

PROPERTIES

Form

Liquid

Buffer

PBS, 150mM NaCl, 50% Glycerol

Preservative

0.02% Sodium Azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

A synthesized peptide derived from human CYP7B1(Accession O75881), corresponding to amino acid residues R310-L360.

Purification

Purified by affinity chromatography
From serum

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

cytochrome P450 family 7 subfamily B member 1 , CBAS3 , CP7B , SPG5A

Background

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum membrane protein catalyzes the first reaction in the cholesterol catabolic pathway of extrahepatic tissues, which converts cholesterol to bile acids. This enzyme likely plays a minor role in total bile acid synthesis, but may also be involved in the development of atherosclerosis, neurosteroid metabolism and sex hormone synthesis. Mutations in this gene have been associated with hereditary spastic paraplegia (SPG5 or HSP), an autosomal recessive disorder. [provided by RefSeq, Apr 2016]

Database

Research Area

DATA IMAGES

Anti-CYP7B1 antibody used in IHC (Paraffin sections) (IHC-P). GTX04543

GTX04543 IHC-P Image

IHC-P analysis of human mammary cancer and para-carcinoma tissue using GTX04543 CYP7B1 antibody.
Antigen retrieval : Heat mediated citrate buffer
Dilution : 1:100

Anti-CYP7B1 antibody used in IHC (Paraffin sections) (IHC-P). GTX04543

GTX04543 IHC-P Image

IHC-P analysis of human gastric cancer and para-carcinoma tissue using GTX04543 CYP7B1 antibody.
Antigen retrieval : Heat mediated citrate buffer
Dilution : 1:100

Anti-CYP7B1 antibody used in Western Blot (WB). GTX04543

GTX04543 WB Image

WB analysis of LOVO whole cell lysates using GTX04543 CYP7B1 antibody. The lane on the left was treated with blocking peptide.

REFERENCE

There are currently no references for CYP7B1 antibody (GTX04543). Be the first to share your publications with this product.
Submit a Reference

REVIEW

There are currently no reviews for CYP7B1 antibody (GTX04543). Be the first to share your experience with this product.
Submit a Review
Package List Price ($)
$ 399