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Calcipressin 1 antibody

Anti-Calcipressin 1 antibody used in Western Blot (WB). GTX100245
Anti-Calcipressin 1 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX100245

Cat. No. GTX100245

Reference 1

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, ICC/IF, IHC-P

Reactivity

 Human
Package
100 μl ($399),
25 μl ($169)
See all Calcipressin 1 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500-1:3000
ICC/IF 1:100-1:1000
IHC-P Assay dependent
Not tested in other applications.

Calculated MW

28 kDa. ( Note )

Positive Control

HeLa

Predict Reactivity

Pig, Chimpanzee(>80% identity)

PROPERTIES

Form

Liquid

Buffer

PBS, 20% Glycerol

Preservative

0.01% Thimerosal

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human Calcipressin 1. The exact sequence is proprietary.

Purification

Purified by antigen-affinity chromatography.

Conjugation

Unconjugated

RRID

AB_1240729

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

regulator of calcineurin 1 , ADAPT78 , CSP1 , DSC1 , DSCR1 , MCIP1 , RCN1

Background

The protein encoded by this gene interacts with calcineurin A and inhibits calcineurin-dependent signaling pathways, possibly affecting central nervous system development. This gene is located in the minimal candidate region for the Down syndrome phenotype, and is overexpressed in the brain of Down syndrome fetuses. Chronic overexpression of this gene may lead to neurofibrillary tangles such as those associated with Alzheimer disease. Three transcript variants encoding three different isoforms have been found for this gene. [provided by RefSeq]

Database

Research Area

DATA IMAGES

Anti-Calcipressin 1 antibody used in Western Blot (WB). GTX100245

GTX100245 WB Image

Sample (30 ug of whole cell lysate)
A: Hela
12% SDS PAGE
GTX100245 diluted at 1:1000

Anti-Calcipressin 1 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX100245

GTX100245 ICC/IF Image

Calcipressin 1 antibody detects Calcipressin 1 protein at cytoplasm and nucleus by immunofluorescent analysis.
Sample: HeLa cells were fixed in 4% paraformaldehyde at RT for 15 min.
Green: Calcipressin 1 protein stained by Calcipressin 1 antibody (GTX100245) diluted at 1:500.
Blue: Hoechst 33342 staining.

REFERENCE

Application Reference

Deng R et al. Mol Cancer 2020; 19 (1) : 122 Disruption of super-enhancer-driven tumor suppressor gene RCAN1.4 expression promotes the malignancy of breast carcinoma.
Application : IHC-P
Reactivity : Human
Submit a Reference

REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Thimerosal.pdf
Package List Price ($)
$ 399
$ 169