GeneTex
United States (US)

Calcium Sensing Receptor antibody

GTX31574_1210_IHC-P_20180221_18121410_477.jpg
GTX31574_2759_WB_20180221_18121410_960.jpg
GTX31574_1209_IHC-P_20180221_18121410_173.jpg

Cat No. GTX31574

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, IHC-P, ELISA
Reactivity Human, Mouse, Rat
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1 - 2 μg/mL
IHC-P 5 μg/mL
ELISA Assay dependent
Not tested in other applications.

Calculated MW

121 kDa. ( Note )

Positive Control

EL4 Cell Lysate(GTX27183) , Human Kidney Tissue Slide
PROPERTIES

Form

Liquid

Buffer

PBS with 0.02% sodium azide.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

CASR antibody was raised against a 15 amino acid peptide near the amino terminus of human CASR.The immunogen is located within the first 50 amino acids of CASR.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Calcium Sensing Receptor,Car,Eig8,Fhh,Fih,Gprc2A,Hhc,Hhc1,Hypoc1,Nshpt,Pcar1,Hcasr,Casr

Background

The protein encoded by this gene is a G protein-coupled receptor that is expressed in the parathyroid hormone (PTH)-producing chief cells of the parathyroid gland, and the cells lining the kidney tubule. It senses small changes in circulating calcium concentration and couples this information to intracellular signaling pathways that modify PTH secretion or renal cation handling, thus this protein plays an essential role in maintaining mineral ion homeostasis. Mutations in this gene cause familial hypocalciuric hypercalcemia, familial, isolated hypoparathyroidism, and neonatal severe primary hyperparathyroidism. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES
GTX31574_1210_IHC-P_20180221_18121410_477.jpg

GTX31574 IHC-P Image

IHC-P analysis of human kidney tissue using GTX31574 Calcium Sensing Receptor antibody.
Working concentration : 20 μg/ml

GTX31574_2759_WB_20180221_18121410_960.jpg

GTX31574 WB Image

WB analysis of EL4 cell lysate in (A) the absence and (B) the presence of blocking peptide using GTX31574 Calcium Sensing Receptor antibody.
Working concentration : 1 μg/ml

GTX31574_1209_IHC-P_20180221_18121410_173.jpg

GTX31574 IHC-P Image

IHC-P analysis of human kidney tissue using GTX31574 Calcium Sensing Receptor antibody.
Working concentration : 5 μg/ml

Package List Price ($)
$ 329