APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
| Application |
Recommended Dilution |
| 1 - 2 μg/mL |
| 5 μg/mL |
| Assay dependent |
Not tested in other applications.
Calculated MW
Positive Control
EL4 Cell Lysate(GTX27183) , Human Kidney Tissue Slide
PROPERTIES
Form
Liquid
Buffer
PBS
Preservative
0.02% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
CASR antibody was raised against a 15 amino acid peptide near the amino terminus of human CASR.The immunogen is located within the first 50 amino acids of CASR.
Purification
Purified by antigen-affinity chromatography
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
calcium sensing receptor , CAR , EIG8 , FHH , FIH , GPRC2A , HHC , HHC1 , HYPOC1 , NSHPT , PCAR1 , hCasR
Cellular Localization
Cell membrane
Background
The protein encoded by this gene is a G protein-coupled receptor that is expressed in the parathyroid hormone (PTH)-producing chief cells of the parathyroid gland, and the cells lining the kidney tubule. It senses small changes in circulating calcium concentration and couples this information to intracellular signaling pathways that modify PTH secretion or renal cation handling, thus this protein plays an essential role in maintaining mineral ion homeostasis. Mutations in this gene cause familial hypocalciuric hypercalcemia, familial, isolated hypoparathyroidism, and neonatal severe primary hyperparathyroidism. [provided by RefSeq, Jul 2008]
Database
Research Area
DATA IMAGES
|
GTX31574 IHC-P Image
IHC-P analysis of human kidney tissue using GTX31574 Calcium Sensing Receptor antibody.
Working concentration : 20 μg/ml
|
|
|
GTX31574 IHC-P Image
IHC-P analysis of human kidney tissue using GTX31574 Calcium Sensing Receptor antibody.
Working concentration : 5 μg/ml
|
|
|
GTX31574 WB Image
WB analysis of EL4 cell lysate in (A) the absence and (B) the presence of blocking peptide using GTX31574 Calcium Sensing Receptor antibody.
Working concentration : 1 μg/ml
|
REFERENCE
There are currently no references for Calcium Sensing Receptor antibody (GTX31574). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for Calcium Sensing Receptor antibody (GTX31574). Be the first to share your experience with this product.
