APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
Application |
Recommended Dilution |
5 μg/ml |
Not tested in other applications.
Calculated MW
Predict Reactivity
Bovine, Dog, Hamster, Pig, Monkey, Elephant, Gibbon, Gorilla, Horse, Marmoset, Panda(>80% identity)
PROPERTIES
Form
Liquid
Buffer
PBS
Preservative
0.1% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Synthetic 20 amino acid peptide from N-terminal extracellular domain of human CASR.
Purification
Purified by affinity chromatography
Conjugation
Unconjugated
RRID
AB_375924
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
calcium sensing receptor , CAR , CASR , EIG8 , FHH , FIH , GPRC2A , HHC , HHC1 , HYPOC1 , NSHPT , PCAR1 , Calcium Sensing Receptor
Cellular Localization
Cell membrane
Background
The protein encoded by this gene is a plasma membrane G protein-coupled receptor that senses small changes in circulating calcium concentration. The encoded protein couples this information to intracellular signaling pathways that modify parathyroid hormone secretion or renal cation handling, and thus this protein plays an essential role in maintaining mineral ion homeostasis. Mutations in this gene are a cause of familial hypocalciuric hypercalcemia, neonatal severe hyperparathyroidism, and autosomal dominant hypocalcemia. [provided by RefSeq, Aug 2017]
Database
Research Area
DATA IMAGES
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GTX71753 IHC-P Image
IHC-P analysis of human parathyroid tissue using GTX71753 Calcium Sensing Receptor antibody. Antigen retrieval : Heat-induced antigen retrieval
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GTX71753 IHC-P Image
IHC-P analysis of human kidney, diabetes tissue using GTX71753 Calcium Sensing Receptor antibody. Antigen retrieval : Heat-induced antigen retrieval
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GTX71753 IHC-P Image
IHC-P analysis of human parathyroid, adenoma tissue using GTX71753 Calcium Sensing Receptor antibody. Antigen retrieval : Heat-induced antigen retrieval
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GTX71753 IHC-P Image
IHC-P analysis of human thyroid, medullary carcinoma tissue using GTX71753 Calcium Sensing Receptor antibody. Antigen retrieval : Heat-induced antigen retrieval
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GTX71753 IHC-P Image
IHC-P analysis of parathyroid adenoma tissue using GTX71753 Calcium Sensing Receptor antibody.
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REFERENCE
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REVIEW
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