GeneTex
United States (US)

Calpain 3 antibody [C2C3], C-term

GTX102500_WB_19011506_402.jpg

Cat No. GTX102500

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB
Reactivity Human
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500-1:3000
Not tested in other applications.

Calculated MW

94 kDa. ( Note )

Positive Control

HeLa

Predict Reactivity

Mouse, Rat, Rabbit, Sheep, Bovine, Chicken, Pig, Xenopus laevis(>80% identity)
PROPERTIES

Form

Liquid

Buffer

1XPBS, 40% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

2mg/ml(Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant protein encompassing a sequence within the C-terminus region of human Calpain 3. The exact sequence is proprietary.

Purification

Affinity purified by Protein A.

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

CANP3 antibody, CANPL3 antibody, LGMD2 antibody, LGMD2A antibody, MGC10767 antibody, MGC11121 antibody, MGC14344 antibody, MGC4403 antibody, nCL-1 antibody, p94 antibody, CAPN3 antibody, new calpain 1 antibody, calpain-3 antibody, "calpain p94, large [catalytic] subunit antibody", muscle-specific calcium-activated neutral protease 3 large subunit antibody, "calpain, large polypeptide L3 antibody", calpain L3 antibody, calcium-activated neutral proteinase 3 antibody, "calpain 3, (p94) antibody"

Cellular Localization

Cytoplasm

Background

Calpain, a heterodimer consisting of a large and a small subunit, is a major intracellular protease, although its function has not been well established. This gene encodes a muscle-specific member of the calpain large subunit family that specifically binds to titin. Mutations in this gene are associated with limb-girdle muscular dystrophies type 2A. Alternate promoters and alternative splicing result in multiple transcript variants encoding different isoforms and some variants are ubiquitously expressed. [provided by RefSeq]

Database

Research Area

DATA IMAGES
GTX102500_WB_19011506_402.jpg

GTX102500 WB Image

Sample (30 ug of whole cell lysate)
A: Hela
7.5% SDS PAGE
Calpain 3 antibody
GTX102500 diluted at 1:1000

SDS
PBS.pdf
Glycerol.pdf
Thimerosal.pdf
Package List Price ($)
$ 319
$ 169