*Optimal dilutions/concentrations should be determined by the researcher.
Not tested in other applications.
This antibody reacts with full-size calpain 3 (94 kD) plus an additional breakdown product at 60 kD.
Tissue culture supernatant
15mM Sodium azide
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Batch dependent (Please refer to the vial label for the specific concentration.)
Synthetic peptide containing amino acids 355-370 of the human calpain 3 sequence.
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
calpain 3 , CANP3 , CANPL3 , LGMD2 , LGMD2A , LGMDD4 , LGMDR1 , nCL-1 , p94
Calpain, a heterodimer consisting of a large and a small subunit, is a major intracellular protease, although its function has not been well established. This gene encodes a muscle-specific member of the calpain large subunit family that specifically binds to titin. Mutations in this gene are associated with limb-girdle muscular dystrophies type 2A. Alternate promoters and alternative splicing result in multiple transcript variants encoding different isoforms and some variants are ubiquitously expressed. [provided by RefSeq, Jul 2008]
GTX01970 WB Image
WB analysis of human skeletal muscle tissue lysate using GTX01970 Calpain 3 antibody [Calp3c/12A2] and GTX01970 Calpain 3 antibody [Calp3d/2C4].
Lane A : GTX01971
Lane B : GTX01970