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Calpain S1 antibody

Anti-Calpain S1 antibody used in IHC (Paraffin sections) (IHC-P). GTX33058
Anti-Calpain S1 antibody used in IHC (Paraffin sections) (IHC-P). GTX33058
Anti-Calpain S1 antibody used in Western Blot (WB). GTX33058
Anti-Calpain S1 antibody used in IHC (Paraffin sections) (IHC-P). GTX33058

Cat No. GTX33058

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Application

WB, IHC-P

Reactivity

Human, Mouse, Rat
Package
100 μl ($329)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500 - 1:2000
IHC-P 1:50 - 1:200
Not tested in other applications.

Calculated MW

28 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS pH7.3, 0.02% sodium azide, 50% glycerol.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 69-268 of human CAPNS1 (NP_001740.1).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

calpain small subunit 1 , CALPAIN4 , CANP , CANPS , CAPN4 , CDPS , CSS1

Cellular Localization

Cytoplasm,Cell membrane

Background

This gene is a member of the calpain small subunit family. Calpains are calcium-dependent cysteine proteinases that are widely distributed in mammalian cells. Calpains operate as heterodimers, comprising a specific large catalytic subunit (calpain 1 subunit in Calpain I, and calpain 2 subunit in Calpain II), and a common small regulatory subunit encoded by this gene. This encoded protein is essential for the stability and function of both calpain heterodimers, whose proteolytic activities influence various cellular functions including apoptosis, proliferation, migration, adhesion, and autophagy. Calpains have been implicated in neurodegenerative processes, such as myotonic dystrophy. A pseudogene of this gene has been defined on chromosome 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2014]

Database

Research Area

DATA IMAGES

Anti-Calpain S1 antibody used in IHC (Paraffin sections) (IHC-P). GTX33058

GTX33058 IHC-P Image

IHC-P analysis of human colon tissue using GTX33058 Calpain S1 antibody.
Dilution : 1:100

Anti-Calpain S1 antibody used in IHC (Paraffin sections) (IHC-P). GTX33058

GTX33058 IHC-P Image

IHC-P analysis of human esophageal cancer tissue using GTX33058 Calpain S1 antibody.
Dilution : 1:100

Anti-Calpain S1 antibody used in Western Blot (WB). GTX33058

GTX33058 WB Image

WB analysis of various samples using GTX33058 Calpain S1 antibody.
Dilution : 1:1000
Loading : 25μg per lane

Anti-Calpain S1 antibody used in IHC (Paraffin sections) (IHC-P). GTX33058

GTX33058 IHC-P Image

IHC-P analysis of human liver cancer tissue using GTX33058 Calpain S1 antibody.
Dilution : 1:100

REFERENCE

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REVIEW

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Package List Price ($)
$ 329