GeneTex
United States (US)

Calpain S1 antibody

GTX33058_20180530_IHC-P_18121410_666.jpg
GTX33058_20180530_IHC-P_1_18121410_263.jpg
GTX33058_20180530_WB_18121410_271.jpg
GTX33058_20180530_IHC-P_2_18121410_200.jpg

Cat No. GTX33058

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, IHC-P
Reactivity Human, Mouse, Rat
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500 - 1:2000
IHC-P 1:50 - 1:200
Not tested in other applications.

Calculated MW

28 kDa. ( Note )
PROPERTIES

Form

Liquid

Buffer

PBS pH7.3, 0.02% sodium azide, 50% glycerol.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 69-268 of human CAPNS1 (NP_001740.1).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Calpain Small Subunit 1,Calpain4,Canp,Canps,Capn4,Cdps,Css1,Capns1

Background

This gene is a member of the calpain small subunit family. Calpains are calcium-dependent cysteine proteinases that are widely distributed in mammalian cells. Calpains operate as heterodimers, comprising a specific large catalytic subunit (calpain 1 subunit in Calpain I, and calpain 2 subunit in Calpain II), and a common small regulatory subunit encoded by this gene. This encoded protein is essential for the stability and function of both calpain heterodimers, whose proteolytic activities influence various cellular functions including apoptosis, proliferation, migration, adhesion, and autophagy. Calpains have been implicated in neurodegenerative processes, such as myotonic dystrophy. A pseudogene of this gene has been defined on chromosome 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2014]

Database

DATA IMAGES
GTX33058_20180530_IHC-P_18121410_666.jpg

GTX33058 IHC-P Image

IHC-P analysis of human colon tissue using GTX33058 Calpain S1 antibody.
Dilution : 1:100

GTX33058_20180530_IHC-P_1_18121410_263.jpg

GTX33058 IHC-P Image

IHC-P analysis of human esophageal cancer tissue using GTX33058 Calpain S1 antibody.
Dilution : 1:100

GTX33058_20180530_WB_18121410_271.jpg

GTX33058 WB Image

WB analysis of various samples using GTX33058 Calpain S1 antibody.
Dilution : 1:1000
Loading : 25μg per lane

GTX33058_20180530_IHC-P_2_18121410_200.jpg

GTX33058 IHC-P Image

IHC-P analysis of human liver cancer tissue using GTX33058 Calpain S1 antibody.
Dilution : 1:100

Package List Price ($)
$ 329