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Camostat mesylate

Cat No. GTX01523

Package
50 mg ($199)
PRODUCT

Summary

A serine protease inhibitor inhibiting plasmin, kallikrein, thrombin as well as trypsin, which attenuates pancreatic fibrosis. Reduces weight gain and improves metabolism in obese rodent models. In clinical use (in Japan) for pancreatitis. Inhibits influenza virus replication in human tracheal epithelial cells. Reduces infection of Calu-3 lung cells by SARS-CoV-2 (responsible for COVID-19) via inhibition of the serine protease TMPRSS2 required for viral spike protein priming.
CAS No.: 59721-29-8
Physical Properties: Off-white powder
Chemical formula: C₂₀ H ₂₂ N₄O₅•CH₃SO₃H
Molecular weight: 494.5

PROPERTIES

Form

Lyophilized powder

Buffer

Reconstitute with DMSO (50 mg/ml) or Water (50 mg/ml).

Storage

Store desiccated as supplied at -20ºC for up to 2 years. Store solutions at -20ºC for up to 1 month.

Purity

>98% (HPLC); NMR (Conforms)

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

4-(2-(2-(dimethylamino)-2-oxoethoxy)-2-oxoethyl)phenyl 4-guanidinobenzoate, methanesulfonic acid salt , FOY-305 , Foipan

REFERENCE

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Package List Price ($)
$ 199