APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
| Application |
Recommended Dilution |
| 1:500-1:2000 |
| 1:500-1:2000 |
Not tested in other applications.
Calculated MW
PROPERTIES
Form
Liquid
Buffer
0.2μm-filtered PBS
Preservative
No preservative
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
Batch dependent (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Recombinant Human CA12 protein
Purification
Purified by Protein A and Antigen Affinity
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
carbonic anhydrase 12 , CA-XII , CAXII , HsT18816 , T18816
Cellular Localization
Membrane; Single-pass type I membrane protein , Cell membrane
Background
Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. This gene product is a type I membrane protein that is highly expressed in normal tissues, such as kidney, colon and pancreas, and has been found to be overexpressed in 10% of clear cell renal carcinomas. Three transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jun 2014]
Database
Research Area
DATA IMAGES
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GTX02237 WB Image
WB analysis of MCF-7 membrane extracts (Lane A) using GTX02237 Carbonic Anhydrase XII antibody.
Dilution : 1:500
Loading : 20 μg
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GTX02237 IHC-P Image
IHC-P analysis of human kidney tissue section using GTX02237 Carbonic Anhydrase XII antibody.
Dilution : 1:1000
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GTX02237 IHC-P Image
IHC-P analysis of human prostatic carcinoma tissue section using GTX02237 Carbonic Anhydrase XII antibody.
Dilution : 1:1000
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GTX02237 IHC-P Image
IHC-P analysis of human colon carcinoma tissue section using GTX02237 Carbonic Anhydrase XII antibody.
Dilution : 1:1000
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REFERENCE
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REVIEW
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