GeneTex
United States (US)

Carboxypeptidase B2 antibody [13H4]

Carboxypeptidase-B2-antibody-13H4-GTX14757-ELISA-1_18121409_715.jpg
Carboxypeptidase-B2-antibody-13H4-GTX14757-WB-1_18121409_360.jpg

Cat No. GTX14757

Host Mouse
Clonality Monoclonal
Clone Name 13H4
Isotype IgG1
Application WB, ELISA, EIA, sELISA
Reactivity Human
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB Assay dependent
ELISA Assay dependent
EIA Assay dependent
sELISA Assay dependent

Note :

sELISA
Capture: GTX14756, Detection: GTX14757.

Not tested in other applications.

Calculated MW

44.02 kDa. ( Note )
PROPERTIES

Form

Liquid

Buffer

PBS pH 7.4, 0.09 % sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4º C.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Full length native protein (purified) (Human).

Purification

Protein A purified

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Carboxypeptidase B2,Cpu,Pcpb,Tafi,Cpb2

Background

Carboxypeptidases are enzymes that hydrolyze C-terminal peptide bonds. The carboxypeptidase family includes metallo-, serine, and cysteine carboxypeptidases. According to their substrate specificity, these enzymes are referred to as carboxypeptidase A (cleaving aliphatic residues) or carboxypeptidase B (cleaving basic amino residues). The protein encoded by this gene is activated by trypsin and acts on carboxypeptidase B substrates. After thrombin activation, the mature protein downregulates fibrinolysis. Polymorphisms have been described for this gene and its promoter region. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jun 2013]

Database

DATA IMAGES
Carboxypeptidase-B2-antibody-13H4-GTX14757-ELISA-1_18121409_715.jpg

GTX14757 ELISA Image

Titration curves of carboxypeptidase B2 in plasma using antibody pair; captureGTX14756, 200ng/welland GTX? conjugated to HRP. Incubated at room temperature.

Carboxypeptidase-B2-antibody-13H4-GTX14757-WB-1_18121409_360.jpg

GTX14757 WB Image

Detection ofcarboxypeptidease B2 (TAFI)with GTX14757 [13H4] in western blotting (non reducing conditions).

Package List Price ($)
$ 289