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Cardiac Troponin C antibody [1A2]

Cat No. GTX28285

Host

Mouse

Clonality

Monoclonal

Clone Name

1A2

Isotype

IgG2a

Application

WB, ELISA, Purification, Sandwich ELISA

Reactivity

Human
Package
200 μg ($259)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB Assay dependent
ELISA Assay dependent
Purification Assay dependent
Sandwich ELISA Assay dependent

Note :

Sandwich ELISA
Capture : GTX28285, Detection : GTX28286

Not tested in other applications.

Calculated MW

18 kDa. ( Note )

Product Note

No cross-reactivity with cTnT and cTnI. This antibody can recognize TnC also in binary complex with cTnI.

PROPERTIES

Form

Liquid

Buffer

PBS pH 7.4, 0.09 % sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Isolated slow skeletal isoform of TnC .

Purification

Protein A purified

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

troponin C1, slow skeletal and cardiac type , CMD1Z , CMH13 , TN-C , TNC , TNNC

Background

Troponin is a central regulatory protein of striated muscle contraction, and together with tropomyosin, is located on the actin filament. Troponin consists of 3 subunits: TnI, which is the inhibitor of actomyosin ATPase; TnT, which contains the binding site for tropomyosin; and TnC, the protein encoded by this gene. The binding of calcium to TnC abolishes the inhibitory action of TnI, thus allowing the interaction of actin with myosin, the hydrolysis of ATP, and the generation of tension. Mutations in this gene are associated with cardiomyopathy dilated type 1Z. [provided by RefSeq, Oct 2008]

Database

Research Area

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 259