GeneTex
United States (US)

Cardiac Troponin C antibody

GTX33061_20180530_WB_18121410_330.jpg
GTX33061_20180530_IHC-P_18121410_543.jpg
GTX33061_20180530_ICCIF_18121410_353.jpg

Cat No. GTX33061

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, ICC/IF, IHC-P
Reactivity Human, Mouse
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500 - 1:2000
ICC/IF 1:50 - 1:200
IHC-P 1:50 - 1:200
Not tested in other applications.

Calculated MW

18 kDa. ( Note )
PROPERTIES

Form

Liquid

Buffer

PBS pH7.3, 0.02% sodium azide, 50% glycerol.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-160 of human TNNC1 (NP_003271.1).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Troponin C1, Slow Skeletal And Cardiac Type,Cmd1Z,Cmh13,Tn-C,Tnc,Tnnc,Tnnc1

Background

Troponin is a central regulatory protein of striated muscle contraction, and together with tropomyosin, is located on the actin filament. Troponin consists of 3 subunits: TnI, which is the inhibitor of actomyosin ATPase; TnT, which contains the binding site for tropomyosin; and TnC, the protein encoded by this gene. The binding of calcium to TnC abolishes the inhibitory action of TnI, thus allowing the interaction of actin with myosin, the hydrolysis of ATP, and the generation of tension. Mutations in this gene are associated with cardiomyopathy dilated type 1Z. [provided by RefSeq, Oct 2008]

Database

DATA IMAGES
GTX33061_20180530_WB_18121410_330.jpg

GTX33061 WB Image

WB analysis of various samples using GTX33061 Cardiac Troponin C antibody.
Dilution : 1:1000
Loading : 25μg per lane

GTX33061_20180530_IHC-P_18121410_543.jpg

GTX33061 IHC-P Image

IHC-P analysis of human colon carcinoma tissue using GTX33061 Cardiac Troponin C antibody.
Dilution : 1:100

GTX33061_20180530_ICCIF_18121410_353.jpg

GTX33061 ICC/IF Image

ICC/IF analysis of U2OS cell using GTX33061 Cardiac Troponin C antibody.
Blue : DAPI

Package List Price ($)
$ 329