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Cardiac Troponin I antibody [16A11]

Anti-Cardiac Troponin I antibody [16A11] used in ELISA (ELISA). GTX10226
Anti-Cardiac Troponin I antibody [16A11] used in Western Blot (WB). GTX10226

Cat No. GTX10226

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 16A11

Isotype

 IgG1

Application

 WB, IP, ELISA, Immunoassay, IHC, Purification, sELISA

Reactivity

 Human, Rabbit, Goat, Bovine, Cat, Dog, Pig
Package
200 μg ($289)
See all Cardiac Troponin I products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB Assay dependent
IP Assay dependent
ELISA Assay dependent
Immunoassay Assay dependent
IHC Assay dependent
Purification Assay dependent
sELISA Assay dependent

Note :

sELISA
Capture : GTX28289, Detection : GTX10226
Not tested in other applications.

Calculated MW

24.01 kDa. ( Note )

Specificity/Sensitivity

No cross-reactivity with skeletal muscle TnI.

PROPERTIES

Form

Liquid

Buffer

PBS pH 7.4, 0.09 % sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4º C.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Free human cardiac troponin I, native human cardiac troponin complex, or human cardiac troponin I peptides.

Purification

Protein A purified

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

Troponin I3, Cardiac Type , Cmd1Ff , Cmd2A , Cmh7 , Rcm1 , Tnnc1 , Ctni , Tnni3

Background

Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM). [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-Cardiac Troponin I antibody [16A11] used in ELISA (ELISA). GTX10226

GTX10226 ELISA Image

Cardiac troponin I measurements using sandwich immunoassays to determine the total cardiac troponin I in serial blood samples from AMI patient.

Anti-Cardiac Troponin I antibody [16A11] used in Western Blot (WB). GTX10226

GTX10226 WB Image

Detection of cardiac troponin I (cTnI) by Western blotting. After SDS-PAGE cTnI was transferred to a nitrocellulose membrane and probed by Cardiac Troponin I antibody [16A11] (GTX10226) and then by a HRP-conjugated goat anti-mouse IgG antibody. Substrate - diaminobenzidine. Lane 1: 3 ng cTnI; Lane 2: 10 ng cTnI; Lane 3: 30 ng cTnI; Lane 4: 100 ng cTnI.

REFERENCE

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REVIEW

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Package List Price ($)
$ 289