*Optimal dilutions/concentrations should be determined by the researcher.
Not tested in other applications.
Reacts equally with free cardiac troponin I (cTnI) and cTnI forming complexes with other troponincomponents. Not affected by heparin, phosphorylation, oxidation and troponin complex formation.Recognizes an epitope located between amino acid residues 86 and 90 of cTnI. No cross-reactivity withskeletal muscle troponin I. Reactive with cTnI from human, bovine, porcine, goat, canine, rabbit, and feline.Not reactive with cTnI from rat, mouse or fish.
PBS pH 7.4, 0.09% sodium azide
Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.
6 mg/ml (Please refer to the vial label for the specific concentration.)
Native Troponin Complex
Protein A purified
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Troponin I3, Cardiac Type,Cmd1Ff,Cmd2A,Cmh7,Rcm1,Tnnc1,Ctni,Tnni3
Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM). [provided by RefSeq, Jul 2008]