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Cardiac Troponin I antibody [19C7]

Cat. No. GTX28289

Reference 6

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 19C7

Isotype

 IgG2b

Application

 WB, IP, ELISA, Immunoassay, IHC, Purification, Sandwich ELISA

Reactivity

 Human, Mouse, Rat, Rabbit, Goat, Bovine, Cat, Dog, Pig, Fish
Package
200 μg ($399)
See all Cardiac Troponin I products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB Assay dependent
IP Assay dependent
ELISA Assay dependent
Immunoassay Assay dependent
IHC Assay dependent
Purification Assay dependent
Sandwich ELISA Assay dependent

Note :

Sandwich ELISA
Capture : GTX28289, Detection : GTX10226 or Capture : GTX10231, Detection : GTX28289
Not tested in other applications.

Calculated MW

24 kDa. ( Note )

Product Note

No cross-reactivity with skeletal muscle TnI.

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.09% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Free human cardiac troponin I, native human cardiac troponin complex, or human cardiac troponin I peptides.

Purification

Protein A purified

Conjugation

Unconjugated

RRID

AB_373196

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

troponin I3, cardiac type , CMD1FF , CMD2A , CMH7 , RCM1 , TNNC1 , cTnI

Background

Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM). [provided by RefSeq, Jul 2008]

Database

Research Area

REFERENCE

Application Reference

Huang CY et al. J Biomed Sci 2020; 27 (1) : 92 Copy number variant hotspots in Han Taiwanese population induced pluripotent stem cell lines - lessons from establishing the Taiwan human disease iPSC Consortium Bank.
Application : IHC
Reactivity : Human
Garza JT et al. Anal Chem 2017; 89 (24) : 13120-13127 Collection Method of SERS Active Nanoparticles for Sensitive and Precise Measurements.
Jeon CS et al. Advanced Functional Materials. 2013; Virus-Tethered Magnetic Gold Microspheres with Biomimetic Architectures for Enhanced Immunoassays.
Miyazaki Y et al. PLoS One 2012; 7 (4) : e35875 Heart failure-inducible gene therapy targeting protein phosphatase 1 prevents progressive left ventricular remodeling.
Application : WB
Reactivity : Mouse

Clone Reference

Yang X et al. Sensors and Actuators B: Chemical 2018; (Epub) Electrogenerated chemiluminescence biosensor array for the detection of multiple AMI biomarkers.
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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399