PBS pH 7.4, 0.09 % sodium azide
Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4º C.
Free human cardiac troponin I, native human cardiac troponin complex, or human cardiac troponin I peptides.
Protein A purified
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Troponin I3, Cardiac Type , Cmd1Ff , Cmd2A , Cmh7 , Rcm1 , Tnnc1 , Ctni , Tnni3
Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM). [provided by RefSeq, Jul 2008]