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United States (US)

Cardiac Troponin I antibody [8E10]

Cardiac-Troponin-I-antibody-8E10_ELISA_GTX10232-1_19011506_375.jpg
Cardiac-Troponin-I-antibody-8E10_Western blot_GTX10232-1_19011720_944.jpg

Cat No. GTX10232

Host Mouse
Clonality Monoclonal
Clone Name 8E10
Isotype IgG1
Application WB, ELISA, Apuri, IA
Reactivity Human, Rabbit, Goat, Bovine, Cat, Dog, Pig
See all Cardiac Troponin I products
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB Assay dependent
ELISA Assay dependent
Apuri Assay dependent
IA Assay dependent
Not tested in other applications.

Calculated MW

24.01 kDa. ( Note )

Specificity/Sensitivity

No cross-reactivity with skeletal muscle TnI.
PROPERTIES

Form

Liquid

Buffer

PBS pH 7.4, 0.09 % sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4º C.

Concentration

Batch dependent(Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Free human cardiac troponin I, native human cardiac troponin complex, or human cardiac troponin I peptides.

Purification

Protein A purified

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

CMD1FF, CMD2A, CMH7, RCM1, TNNC1, TNNI3, cTnI, troponin I3, cardiac type, Cardiac Troponin I

Background

Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM). [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES
Cardiac-Troponin-I-antibody-8E10_ELISA_GTX10232-1_19011506_375.jpg

GTX10232 ELISA Image

Titration of human serum in two albumin sandwich immunoassays. Human Albumin antibody [15C7] (GTX10241) for capture and Human Albumin antibody [1A9] (GTX10242) for detection
Cardiac-Troponin-I-antibody-8E10_Western blot_GTX10232-1_19011720_944.jpg

GTX10232 WB Image

Recognition of the dephospho- and phospho- forms of human cardiac troponin I. A. Cardiac Troponin I antibody [10B11] (GTX10225); B. Cardiac Troponin I antibody [8E10] (GTX10232)
Package List Price ($)
$ 289