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Cardiac Troponin I antibody [C5]

Cat. No. GTX10233

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 C5

Isotype

 IgG2b

Application

 WB, IP, Immunoassay, IHC, Purification

Reactivity

 Human, Mouse, Rat, Rabbit, Goat, Bovine, Cat, Dog, Pig, Fish
Package
200 μg ($399)
See all Cardiac Troponin I products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB Assay dependent
IP Assay dependent
Immunoassay Assay dependent
IHC Assay dependent
Purification Assay dependent
Not tested in other applications.

Calculated MW

24 kDa. ( Note )

Product Note

Cross-reactivity with skeletal TnI is more than 50%.

PROPERTIES

Form

Liquid

Buffer

PBS pH7.4

Preservative

0.09% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Free human cardiac troponin I, native human cardiac troponin complex, or human cardiac troponin I peptides.

Purification

Protein A purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

troponin I3, cardiac type , CMD1FF , CMD2A , CMH7 , RCM1 , TNNC1 , cTnI

Background

Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM). [provided by RefSeq, Jul 2008]

Database

Research Area

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399