GeneTex
United States (US)

Cardiac Troponin I antibody [M46]

Cat No. GTX10238

Host Mouse
Clonality Monoclonal
Clone Name M46
Isotype IgG1
Application WB, Apuri, IA
Reactivity Human
APPLICATION

Calculated MW

24 kDa. ( Note )

Specificity/Sensitivity

Reacts with free cardiac troponin I (cTnI) and cTnI forming complexes with other troponin components (in the presence of 5 mM EDTA). Not affected by heparin, phosphorylation, oxidation and troponin complex formation. Does not cross-react with skeletal muscle troponin I and <10 % with skeletal troponin I. Epitope : 130-145 of human cardiac Troponin I.
PROPERTIES

Form

Liquid

Buffer

PBS pH 7.4, 0.09 % sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.

Concentration

2.9mg/ml(Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Free human cardiac troponin I, native human cardiac troponin complex, or human cardiac troponin I peptides.

Purification

Protein A purified
Purity tested by electrophoresis.

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Background

Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity. It also binds to actin and tropomyosin.

Database

Research Area

Package List Price ($)
$ 289