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Cardiac Troponin T antibody [1C11]

Anti-Cardiac Troponin T antibody [1C11] used in Immunohistochemistry (IHC). GTX28295

Cat. No. GTX28295

Reference 12

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 1C11

Isotype

 IgG1

Application

 WB, ICC/IF, FACS, ELISA, Immunoassay, IHC, Purification, Sandwich ELISA

Reactivity

 Human, Mouse
Package
200 μg ($399)
See all Cardiac Troponin T products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB Assay dependent
ICC/IF Assay dependent
FACS Assay dependent
ELISA Assay dependent
Immunoassay Assay dependent
IHC Assay dependent
Purification Assay dependent
Sandwich ELISA Assay dependent

Note :

Immunoassay
Best capture antibodies for BIAcore.

Sandwich ELISA
Capture : GTX28295, Detection : GTX28296/GTX10222/GTX14541 or Capture : GTX10223, Detection : GTX28295
Not tested in other applications.

Calculated MW

36 kDa. ( Note )

Product Note

No cross-reactivity with skeletal TnT.

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.09% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Free human cTnT

Purification

Protein A purified

Conjugation

Unconjugated

RRID

AB_385658

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

troponin T2, cardiac type , CMD1D , CMH2 , CMPD2 , LVNC6 , RCM3 , TnTC , cTnT

Background

The protein encoded by this gene is the tropomyosin-binding subunit of the troponin complex, which is located on the thin filament of striated muscles and regulates muscle contraction in response to alterations in intracellular calcium ion concentration. Mutations in this gene have been associated with familial hypertrophic cardiomyopathy as well as with dilated cardiomyopathy. Transcripts for this gene undergo alternative splicing that results in many tissue-specific isoforms, however, the full-length nature of some of these variants has not yet been determined. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-Cardiac Troponin T antibody [1C11] used in Immunohistochemistry (IHC). GTX28295

GTX28295 IHC Image

REFERENCE

Application Reference

Takaoka N et al. PLoS One 2024; 19 (1) : e0297443 Rat hair-follicle-associated pluripotent (HAP) stem cells can differentiate into atrial or ventricular cardiomyocytes in culture controlled by specific supplementation.
Saito Y et al. Front Cardiovasc Med 2023; 10 : 1261330 In vivo tracking transplanted cardiomyocytes derived from human induced pluripotent stem cells using nuclear medicine imaging.
Yukihiro Saito et al. Stem Cell Res Ther 2022; 13 (1) : 141 Enhancement of pacing function by HCN4 overexpression in human pluripotent stem cell-derived cardiomyocytes.
Application : ICC/IF
Xu Y et al. Nat Commun 2021; 12 (1) : 2407 Convergent synthesis of diversified reversible network leads to liquid metal-containing conductive hydrogel adhesives.
Williams AL et al. Physiol Genomics 2018; 50 (7) : 479-494 HIF1 mediates a switch in pyruvate kinase isoforms after myocardial infarction.
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Application Reference
Takaoka N et al. PLoS One 2024; 19 (1):e0297443 Rat hair-follicle-associated pluripotent (HAP) stem cells can differentiate into atrial or ventricular cardiomyocytes in culture controlled by specific supplementation.
Saito Y et al. Front Cardiovasc Med 2023; 10:1261330 In vivo tracking transplanted cardiomyocytes derived from human induced pluripotent stem cells using nuclear medicine imaging.
Yukihiro Saito et al. Stem Cell Res Ther 2022; 13 (1):141 Enhancement of pacing function by HCN4 overexpression in human pluripotent stem cell-derived cardiomyocytes.
Application : ICC/IF
Xu Y et al. Nat Commun 2021; 12 (1):2407 Convergent synthesis of diversified reversible network leads to liquid metal-containing conductive hydrogel adhesives.
Williams AL et al. Physiol Genomics 2018; 50 (7):479-494 HIF1 mediates a switch in pyruvate kinase isoforms after myocardial infarction.
Hoffman RM et al. Methods Mol Biol 2018; 1842:241-254 Beating Heart Cells from Hair-Follicle-Associated Pluripotent (HAP) Stem Cells.
Application : IHC
Reactivity : Mouse
Hoffman RM et al. Methods Mol Biol 2018; (Epub) Human Hair Follicle Associated-Pluripotent (hHAP) Stem Cells Differentiate to Cardiac Muscle Cells.
Application : ICC/IF
Reactivity : Human
Lao S et al. Mol Med Rep 2017; 16 (1):507-514 A comparative study of the influence of two types of PHEMA stents on the differentiation of ASCs to myocardial cells.
Application : WB
Reactivity : Human
Shirai K et al. J Cell Biochem 2016; Hypoxia Enhances Differentiation of Hair Follicle-Associated-Pluripotent (HAP) Stem Cells to Cardiac-Muscle Cells.
Application : ICC/IF, FACS
Reactivity : Mouse
Yashiro M et al. Methods Mol Biol 2016; 1453:151-9 Protocols for Efficient Differentiation of Hair Follicle-Associated Pluripotent (HAP) Stem Cells to Beating Cardiac Muscle Cells.
Application : ICC/IF
Reactivity : Mouse
Yamazaki A et al. Cell Cycle 2016;:43107 Early-age-dependent selective decrease of differentiation potential of hair-follicle-associated pluripotent (HAP) stem cells to beating cardiac-muscle cells.
Application : ICC/IF, ELISA
Reactivity : Mouse
Yamazaki A et al. Cell Cycle 2016; 15 (5) * directs hair follicle-associated pluripotent (hap) stem cells to differentiate in vitro to cardiac muscle cells which can be induced to form beating heart-muscle tissue sheets.
Application : ICC/IF
Reactivity : Mouse
SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399