GeneTex
United States (US)

Caspase 10 antibody

Cat No. GTX30487

Host Rabbit
Clonality Polyclonal
Application WB
Reactivity Human
APPLICATION

Application Note

Western blot - Use at 1:500 to 1:1,000 dilution. However, the investigator should determine the optimal dilution for a specific application such as immunohistochemistry.

Calculated MW

59 kDa. ( Note )

Specificity/Sensitivity

Reacts with the N terminus of all isoforms of human Caspase-10
PROPERTIES

Form

Liquid

Buffer

PBS containing 0.02% sodium azide.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1mg/ml(Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Synthetic peptide: ISAQTPRPPMRRWSSVS, corresponding to amino acids 505 -521 of Human Caspase 10.

Purification

IgG

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Caspase 10, ALPS2, Caspase10, 137215, MCH4, CASP10, FLICE2, Q92851, 843

Background

Caspases are death effector domain-containing cysteine aspartases presumed to be at or near the apex of apoptotic signaling pathways. All known isoforms of caspase-10 are abundantly expressed in fetal lung, kidney, and skeletal muscle but are very poorly expressed or absent in these tissues in the adult, implying a possible role for the caspase-10 family in fetal development

Database

Research Area

Package List Price ($)
$ 289