0.01M PBS pH7.4, 1% BSA, 15 mM sodium azide
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
~1 mg/ml (Please refer to the vial label for the specific concentration.)
recombinant p30 subunit of mouse caspase 11.
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
caspase 4, apoptosis-related cysteine peptidase , CASP-11 , CASP-4 , Casp11 , Caspl , ich-3
Cytoplasm, cytosol,Cytoplasm,Endoplasmic reticulum membrane,Mitochondrion,Secreted
Caspase 11 (also known as ICH3) gene encodes two protein products of 38 and 43 kDa that belong to the Ced3/ICE family of cystein proteases. Caspase 11 is an _x001C_upstream_x001D_ caspase with a long prodomain. It undergoes a cleavage upon activation, leading to p20 and p10 subunits. Monoclonal antibodies reacting specifically with caspase 11 are useful tool for the study of the protease network, involved in development and regulation, governing the life and death of cells and tissues.