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Caspase 11 antibody [17D9]

Cat No. GTX10454

Host Rat
Clonality Monoclonal
Clone Name 17D9
Isotype IgG2a
Application WB, IHC-Fr, IP
Reactivity Mouse
Package
100 μl ($389)
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 5-10 μg/ml
IHC-Fr Assay dependent
IP Assay dependent
Not tested in other applications.

Calculated MW

43 kDa. ( Note )

Positive Control

EL4
PROPERTIES

Form

Liquid

Buffer

0.01M PBS pH7.4, 1% BSA, 15 mM sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

~1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Mouse

Immunogen

recombinant p30 subunit of mouse caspase 11.

Purification

Purified immunoglobulin

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

caspase 4, apoptosis-related cysteine peptidase , CASP-11 , CASP-4 , Casp11 , Caspl , ich-3

Cellular Localization

Cytoplasm, cytosol,Cytoplasm,Endoplasmic reticulum membrane,Mitochondrion,Secreted

Background

Caspase 11 (also known as ICH3) gene encodes two protein products of 38 and 43 kDa that belong to the Ced3/ICE family of cystein proteases. Caspase 11 is an _x001C_upstream_x001D_ caspase with a long prodomain. It undergoes a cleavage upon activation, leading to p20 and p10 subunits. Monoclonal antibodies reacting specifically with caspase 11 are useful tool for the study of the protease network, involved in development and regulation, governing the life and death of cells and tissues.

Database

Research Area

REFERENCE
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REVIEW
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Package List Price ($)
$ 389