GeneTex
United States (US)

Caspase 14 antibody

GTX33063_20180530_ICCIF_18121410_747.jpg
GTX33063_20180530_WB_18121410_793.jpg

Cat No. GTX33063

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, ICC/IF
Reactivity Human
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500 - 1:2000
ICC/IF 1:10 - 1:100
Not tested in other applications.

Calculated MW

28 kDa. ( Note )
PROPERTIES

Form

Liquid

Buffer

PBS pH7.3, 0.02% sodium azide, 50% glycerol.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-242 of human CASP14 (NP_036246.1).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Caspase 14,Arci12,Casp14

Background

This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This caspase has been shown to be processed and activated by caspase 8 and caspase 10 in vitro, and by anti-Fas agonist antibody or TNF-related apoptosis inducing ligand in vivo. The expression and processing of this caspase may be involved in keratinocyte terminal differentiation, which is important for the formation of the skin barrier. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES
GTX33063_20180530_ICCIF_18121410_747.jpg

GTX33063 ICC/IF Image

ICC/IF analysis of HeLa cell using GTX33063 Caspase 14 antibody.
Blue : DAPI

GTX33063_20180530_WB_18121410_793.jpg

GTX33063 WB Image

WB analysis of various samples using GTX33063 Caspase 14 antibody.
Dilution : 1:1000
Loading : 25μg per lane

Package List Price ($)
$ 329