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Caspase 2 antibody [18E809.3]

Anti-Caspase 2 antibody [18E809.3] used in Western Blot (WB). GTX13870

Cat. No. GTX13870

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 18E809.3

Isotype

 IgM

Application

 WB

Reactivity

 Human
Package
200 μl ($399)
See all Caspase 2 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500 - 1:1000
Not tested in other applications.

Calculated MW

51 kDa. ( Note )

Product Note

This antibody will cross-react with mouse and rat Caspase-2, based on BLAST.

Predict Reactivity

Mouse, Rat(>80% identity)

PROPERTIES

Form

Liquid

Buffer

Ascites diulted with PBS, 0.2% Gelatin

Preservative

0.05% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

A peptide corresponding to amino acids 400-450 of human Caspase-2 was used as immunogen. GenBank no NP_116764.

Purification

Unpurified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

caspase 2 , CASP-2 , ICH1 , NEDD-2 , NEDD2 , PPP1R57

Background

This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. The proteolytic cleavage of this protein is induced by a variety of apoptotic stimuli. Alternative splicing of this gene results in multiple transcript variants that encode different isoforms. [provided by RefSeq]

Database

Research Area

DATA IMAGES

Anti-Caspase 2 antibody [18E809.3] used in Western Blot (WB). GTX13870

GTX13870 WB Image

WB analysis of HL-60 cell lysate using GTX13870 Caspase 2 antibody [18E809.3].
Dilution : 1:1000
Loading : 20μg

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399