GeneTex
United States (US)

Caspase 2 antibody

Anti-Caspase 2 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX31699
Anti-Caspase 2 antibody used in Western Blot (WB). GTX31699

Cat No. GTX31699

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, ICC/IF, ELISA
Reactivity Human, Mouse
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1 μg/mL
ICC/IF 2 μg/mL
ELISA Assay dependent
Not tested in other applications.

Calculated MW

51 kDa. ( Note )

Positive Control

A20 Cell Lysate(GTX27180) , Human Kidney Tissue Lysate(GTX29995) , Human Thymus Tissue Lysate

Specificity/Sensitivity

Depending on cell lines or tissues used, other cleavage products may be observed.
PROPERTIES

Form

Liquid

Buffer

PBS with 0.02% sodium azide.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Caspase-2 antibody was raised against a 16 amino acid synthetic peptide from the amino-terminus of human Caspase-2.The immunogen is located within the first 50 amino acids of Caspase-2.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Caspase 2,Casp-2,Ich1,Nedd-2,Nedd2,Ppp1R57,Casp2

Background

This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Caspases mediate cellular apoptosis through the proteolytic cleavage of specific protein substrates. The encoded protein may function in stress-induced cell death pathways, cell cycle maintenance, and the suppression of tumorigenesis. Increased expression of this gene may play a role in neurodegenerative disorders including Alzheimer's disease, Huntington's disease and temporal lobe epilepsy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011]

Database

Research Area

DATA IMAGES
Anti-Caspase 2 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX31699

GTX31699 ICC/IF Image

ICC/IF analysis of A-20 cells using GTX31699 Caspase 2 antibody.
Working concentration : 2 μg/ml

Anti-Caspase 2 antibody used in Western Blot (WB). GTX31699

GTX31699 WB Image

WB analysis of (A) human thymus tissue and (B) human kidney lysate using GTX31699 Caspase 2 antibody.
Working concentration : 1 μg/ml

Package List Price ($)
$ 329