APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
| Application |
Recommended Dilution |
| 1 μg/mL |
| 2 μg/mL |
| Assay dependent |
Not tested in other applications.
Calculated MW
Positive Control
A20 Cell Lysate(GTX27180) , Human Kidney Tissue Lysate(GTX29995) , Human Thymus Tissue Lysate
Product Note
Depending on cell lines or tissues used, other cleavage products may be observed.
PROPERTIES
Form
Liquid
Buffer
PBS
Preservative
0.02% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Caspase-2 antibody was raised against a 16 amino acid synthetic peptide from the amino-terminus of human Caspase-2.The immunogen is located within the first 50 amino acids of Caspase-2.
Purification
Purified by antigen-affinity chromatography
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
caspase 2 , CASP-2 , ICH1 , NEDD-2 , NEDD2 , PPP1R57
Background
This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Caspases mediate cellular apoptosis through the proteolytic cleavage of specific protein substrates. The encoded protein may function in stress-induced cell death pathways, cell cycle maintenance, and the suppression of tumorigenesis. Increased expression of this gene may play a role in neurodegenerative disorders including Alzheimer's disease, Huntington's disease and temporal lobe epilepsy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011]
Database
Research Area
DATA IMAGES
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GTX31699 ICC/IF Image
ICC/IF analysis of A-20 cells using GTX31699 Caspase 2 antibody.
Working concentration : 2 μg/ml
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GTX31699 WB Image
WB analysis of (A) human thymus tissue and (B) human kidney lysate using GTX31699 Caspase 2 antibody.
Working concentration : 1 μg/ml
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REFERENCE
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REVIEW
There are currently no reviews for Caspase 2 antibody (GTX31699). Be the first to share your experience with this product.
