GeneTex
United States (US)

Caspase 2 (cleaved Gly170) antibody

Caspase-2-cleaved-Gly170-antibody-GTX86956-WB-1_18121409_186.jpg

Cat No. GTX86956

Host Rabbit
Clonality Polyclonal
Application WB, ELISA
Reactivity Human
APPLICATION

Application Note

We recommend the following starting dilutions:

WB: 1:500~1:1000
ELISA: 1:40000

Optimal dilutions should be determined experimentally by the end user.

Calculated MW

18 kDa. ( Note )

Specificity/Sensitivity

Caspase 2 (p18,Cleaved-Gly170) Antibody detects endogenous levels of fragment of activated Caspase 2 resulting from cleavage adjacent to Gly170.
PROPERTIES

Form

Liquid

Buffer

Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

The antiserum was produced against synthesized peptide derived from human Caspase 2.

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Caspase 2,Casp-2,Ich1,Nedd-2,Nedd2,Ppp1R57,Casp2

Background

Involved in the activation cascade of caspases responsible for apoptosis execution. Might function by either activating some proteins required for cell death or inactivating proteins necessary for cell survival.

Database

Research Area

DATA IMAGES
Caspase-2-cleaved-Gly170-antibody-GTX86956-WB-1_18121409_186.jpg

GTX86956 WB Image

Western blot analysis of extracts from Jurkat cells, treated with etoposide 25uM 24h, using Caspase 2 (p18,Cleaved-Gly170) Antibody. The lane on the right is treated with the synthesized peptide.

Package List Price ($)
$ 339