GeneTex
United States (US)

Caspase 2L antibody

Cat No. GTX27979

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, IHC-P, IHC-Fr, IP
Reactivity Human, Mouse, Rat
APPLICATION

Calculated MW

51 kDa. ( Note )

Positive Control

HL-60 and Jurkat

Specificity/Sensitivity

Reacts with caspase-2L p12 subunit
PROPERTIES

Form

Liquid

Buffer

PBS with 0.1% sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.

Concentration

0.2 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Synthetic peptide (Human) (C terminal).

Purification

IgG fraction

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Caspase 2,Casp-2,Ich1,Nedd-2,Nedd2,Ppp1R57,Casp2

Background

Caspase-2 (also designated Nedd-2/ICH-1) can be alternatively spliced to produce two distinct Caspase-2 mRNA species. One mRNA species encodes a protein of 435 amino acids in length and the mRNA splice variant encodes a 312 amino acid protein. The larger protein, Caspase-2L, in an over expressed state, leads to programmed cell death. Conversely the over expression of Caspase-2S protein, a truncated version of Caspase-2L, has been shown to suppress cell death induced by serum deprivation (5).

Database

Research Area

Package List Price ($)
$ 319