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Caspase 3 antibody [5H10]

Anti-Caspase 3 antibody [5H10] used in IHC (Paraffin sections) (IHC-P). GTX34166
Anti-Caspase 3 antibody [5H10] used in IHC (Paraffin sections) (IHC-P). GTX34166
Anti-Caspase 3 antibody [5H10] used in IHC (Paraffin sections) (IHC-P). GTX34166

Cat. No. GTX34166

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 5H10

Isotype

 IgG1

Application

 IHC-P

Reactivity

 Human, Mouse
Package
100 μl ($399)
See all Caspase 3 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-P 1:100-1:200
Not tested in other applications.

Calculated MW

32 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 0.5% BSA, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

synthetic peptide derived from Caspase-3 at 20-100 aa.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

CASP3,CPP32,CPP32B,SCA1,caspase 3,Caspase 3

Cellular Localization

Cytoplasm

Background

The protein encoded by this gene is a cysteine-aspartic acid protease that plays a central role in the execution-phase of cell apoptosis. The encoded protein cleaves and inactivates poly(ADP-ribose) polymerase while it cleaves and activates sterol regulatory element binding proteins as well as caspases 6, 7, and 9. This protein itself is processed by caspases 8, 9, and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease. [provided by RefSeq, Aug 2017]

Database

Research Area

DATA IMAGES

Anti-Caspase 3 antibody [5H10] used in IHC (Paraffin sections) (IHC-P). GTX34166

GTX34166 IHC-P Image

IHC-P analysis of mouse liver tissue using GTX34166 Caspase 3 antibody [5H10].
Dilution : 1:200

Anti-Caspase 3 antibody [5H10] used in IHC (Paraffin sections) (IHC-P). GTX34166

GTX34166 IHC-P Image

IHC-P analysis of human skin tissue using GTX34166 Caspase 3 antibody [5H10].
Dilution : 1:200

Anti-Caspase 3 antibody [5H10] used in IHC (Paraffin sections) (IHC-P). GTX34166

GTX34166 IHC-P Image

IHC-P analysis of human prostate tissue using GTX34166 Caspase 3 antibody [5H10].
Dilution : 1:200

REFERENCE

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REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399