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Caspase 3 antibody [CPP32 4-1-18]

Anti-Caspase 3 antibody [CPP32 4-1-18] used in Western Blot (WB). GTX30246
Anti-Caspase 3 antibody [CPP32 4-1-18] used in Western Blot (WB). GTX30246
Anti-Caspase 3 antibody [CPP32 4-1-18] used in IHC (Paraffin sections) (IHC-P). GTX30246
Anti-Caspase 3 antibody [CPP32 4-1-18] used in IHC (Paraffin sections) (IHC-P). GTX30246
Anti-Caspase 3 antibody [CPP32 4-1-18] used in IHC (Paraffin sections) (IHC-P). GTX30246

Cat. No. GTX30246

Reference 4

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 CPP32 4-1-18

Isotype

 IgG2a

Application

 WB, IHC-P

Reactivity

 Human, Mouse, Rat
Package
200 μl ($419)
See all Caspase 3 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500 - 1:1000
IHC-P 1:200 - 1:500
Not tested in other applications.

Calculated MW

32 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Full-length recombinant human Caspase 3 [UniProt# P42574]

Purification

Protein G purified

Conjugation

Unconjugated

RRID

AB_367939

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

caspase 3 , CPP32 , CPP32B , SCA-1

Cellular Localization

Cytoplasm

Background

This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 6, 7 and 9, and the protein itself is processed by caspases 8, 9 and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease. Alternative splicing of this gene results in two transcript variants that encode the same protein. [provided by RefSeq]

Database

Research Area

DATA IMAGES

Anti-Caspase 3 antibody [CPP32 4-1-18] used in Western Blot (WB). GTX30246

GTX30246 WB Image

WB analysis of HEK293 cell lysate using GTX30246 Caspase 3 antibody [CPP32 4-1-18].

Anti-Caspase 3 antibody [CPP32 4-1-18] used in Western Blot (WB). GTX30246

GTX30246 WB Image

WB analysis of HEK293 cell lysate using GTX30246 Caspase 3 antibody [CPP32 4-1-18].
Lanes 1 : inactive Caspase
Lane 2 : active Caspase

Anti-Caspase 3 antibody [CPP32 4-1-18] used in IHC (Paraffin sections) (IHC-P). GTX30246

GTX30246 IHC-P Image

IHC-P analysis of human spleen tissue using GTX30246 Caspase 3 antibody [CPP32 4-1-18].
Dilution : 1:200

Anti-Caspase 3 antibody [CPP32 4-1-18] used in IHC (Paraffin sections) (IHC-P). GTX30246

GTX30246 IHC-P Image

IHC-P analysis of human bladder tissue using GTX30246 Caspase 3 antibody [CPP32 4-1-18].
Dilution : 1:300

Anti-Caspase 3 antibody [CPP32 4-1-18] used in IHC (Paraffin sections) (IHC-P). GTX30246

GTX30246 IHC-P Image

IHC-P analysis of rat tongue base tissue using GTX30246 Caspase 3 antibody [CPP32 4-1-18].
Antigen retrieval : Citrate buffer pH 6

REFERENCE

Application Reference

Mervat M Youssef et al. J Oral Biol Craniofac Res 2021; 11 (3) : 386-392 Impact of biosynthesized silver nanoparticles cytotoxicity on dental pulp of albino rats (histological and immunohistochemical study).
Application : IHC-P
Reactivity : Rat
Eltamany EE et al. Antioxidants (Basel) 2021; 10 (6)
Application : IHC-P
Reactivity : Rat
Hassan HM et al. Am J Cancer Res 2021; 11 (2) : 350-369 Adamantane-linked isothiourea derivatives suppress the growth of experimental hepatocellular carcinoma via inhibition of TLR4-MyD88-NF-κB signaling.
Application : IHC-P
Reactivity : Rat
Andhea Pradhita et al. AIP Conference Proceedings 2019; 2193 : 40006 GnRH receptor expression and endometrial cell proliferation of Macaca nemestrina after administration of GnRH agonist in controlled ovarian stimulation procedures.
Application : IHC-P
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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 419