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Caspase 3 antibody

Anti-Caspase 3 antibody used in IHC (Paraffin sections) (IHC-P). GTX73090
Anti-Caspase 3 antibody used in Western Blot (WB). GTX73090

Cat No. GTX73090

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Application

WB, IHC-P, IP, IHC

Reactivity

Human, Mouse, Rat, Rabbit
Package
500 μl ($319)

APPLICATION

Application Note

For IHC-P: Use at a dilution of 1:1,000. For IP: Use at a dilution of 1:2,000. For WB: Use at a dilution of 1:500. Optimal dilutions/concentrations should be determined by the researcher.

Calculated MW

32 kDa. ( Note )

Positive Control

Jurkat Cells, Tonsil

PROPERTIES

Form

Liquid

Buffer

10mM Phosphate-buffered saline containing 0.2% BSA and 0.1% sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant full length human caspase 3 protein.

Purification

Protein A affinity purified

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

Caspase 3 , Cpp32 , Cpp32B , Sca-1 , Casp3

Cellular Localization

Cytoplasmic

Background

Caspase 3 is ubiquitously expressed and like other caspases is synthesized as an inactive (32 kD) proenzyme. Recent studies have implicated that Caspase 3 is associated with the induction of apoptosis. Activation of Caspase 3 occurs in response to variety of apoptotic inducers including Fas mediated apoptosis. Upon activation, Caspase 3 is cleaved at Asp28-Ser29 and Asp175-Ser176, thereby generating two subunits of 17 kD and 12 kD, respectively.

Database

Research Area

DATA IMAGES

Anti-Caspase 3 antibody used in IHC (Paraffin sections) (IHC-P). GTX73090

GTX73090 IHC-P Image

The IHC-P analysis of Caspase 3 antibody was published by Wu KJ and colleagues in the journal Evid Based Complement Alternat Med in 2012.PMID: 23304209

Anti-Caspase 3 antibody used in Western Blot (WB). GTX73090

GTX73090 WB Image

The WB analysis of Caspase 3 antibody was published by Wu KJ and colleagues in the journal Evid Based Complement Alternat Med in 2012.PMID: 23304209

REFERENCE

REVIEW

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SDS
Sodium Azide.pdf
Package List Price ($)
$ 319