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Caspase 5 antibody

Anti-Caspase 5 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX31701
Anti-Caspase 5 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX31701
Anti-Caspase 5 antibody used in Western Blot (WB). GTX31701

Cat No. GTX31701

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Application

WB, ICC/IF, ELISA

Reactivity

Human, Mouse
Package
100 μg ($339)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 0.5 - 2 μg/mL
ICC/IF 2 μg/mL
ELISA Assay dependent
Not tested in other applications.

Calculated MW

50 kDa. ( Note )

Positive Control

Ramos Cell Lysate(GTX23955) , P815 Cell Lysate(GTX27185) , P815 Cell Slide(GTX25547)

Specificity/Sensitivity

Depending on cell lines or tissues used, other cleavage products may be observed.

PROPERTIES

Form

Liquid

Buffer

PBS with 0.02% sodium azide.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Caspase-5 antibody was raised against a 14 amino acid synthetic peptide from the center of human Caspase-5.The immunogen is located within amino acids 170 - 220 of Caspase-5.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

caspase 5 , ICE(rel)III , ICEREL-III , ICH-3

Background

This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. Overexpression of the active form of this enzyme induces apoptosis in fibroblasts. Max, a central component of the Myc/Max/Mad transcription regulation network important for cell growth, differentiation, and apoptosis, is cleaved by this protein; this process requires Fas-mediated dephosphorylation of Max. The expression of this gene is regulated by interferon-gamma and lipopolysaccharide. Alternatively spliced transcript variants have been identified for this gene. [provided by RefSeq, Aug 2010]

Database

Research Area

DATA IMAGES

Anti-Caspase 5 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX31701

GTX31701 ICC/IF Image

ICC/IF analysis of P815 cells using GTX31701 Caspase 5 antibody.
Working concentration : 2 μg/ml

Anti-Caspase 5 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX31701

GTX31701 ICC/IF Image

ICC/IF analysis of P815 cells using GTX31701 Caspase 5 antibody.
Working concentration : 2 μg/ml

Anti-Caspase 5 antibody used in Western Blot (WB). GTX31701

GTX31701 WB Image

WB analysis of Ramos cell lysate using GTX31701 Caspase 5 antibody.
Working concentration : (A) 0.5, (B) 1, and (C) 2 μg/ml

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 339