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Caspase 6 antibody [GT1155]

Recombinant antibody Orthogonal
Anti-Caspase 6 antibody [GT1155] used in Western Blot (WB). GTX01098
Anti-Caspase 6 antibody [GT1155] used in Western Blot (WB). GTX01098
Anti-Caspase 6 antibody [GT1155] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX01098

Cat. No. GTX01098

Reference 2

Host

 Rabbit

Clonality

 Monoclonal

Clone Name

 GT1155

Isotype

 IgG

Application

 WB, ICC/IF

Reactivity

 Human, Mouse
Package
100 μl ($419)
See all Caspase 6 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500 - 1:2000
ICC/IF 1:50 - 1:200
Not tested in other applications.

Calculated MW

33 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

A synthesized peptide derived from human Caspase-6.

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

RRID

AB_2885213

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

caspase 6 , MCH2

Cellular Localization

Cytoplasm

Background

This gene encodes a member of the cysteine-aspartic acid protease (caspase) family of enzymes. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic acid residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein is processed by caspases 7, 8 and 10, and is thought to function as a downstream enzyme in the caspase activation cascade. Alternative splicing of this gene results in multiple transcript variants that encode different isoforms. [provided by RefSeq, Oct 2015]

Database

Research Area

DATA IMAGES

Anti-Caspase 6 antibody [GT1155] used in Western Blot (WB). GTX01098

GTX01098 WB Image

Orthogonal

Untreated (–) and treated (+) Jurkat whole cell extracts (30 μg) were separated by 15% SDS-PAGE, and the membrane was blotted with Caspase 6 antibody [GT1155] (GTX01098) diluted at 1:500. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.

Anti-Caspase 6 antibody [GT1155] used in Western Blot (WB). GTX01098

GTX01098 WB Image

WB analysis of various samples using GTX01098 Caspase 6 antibody [GT1155].
Dilution : 1:1000
Loading : 25 μg

Anti-Caspase 6 antibody [GT1155] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX01098

GTX01098 ICC/IF Image

ICC/IF analysis of NIH3T3 cells using GTX01098 Caspase 6 antibody [GT1155].
Orange: Primary antibody
Blue: DAPI

REFERENCE

Application Reference

Lin YC et al. Int J Mol Sci 2020; 21 (12) Nifedipine Exacerbates Lipogenesis in the Kidney via KIM-1, CD36, and SREBP Upregulation: Implications from an Animal Model for Human Study.
Lin YC et al. Int J Mol Sci 2019; 20 (7) Nifedipine Modulates Renal Lipogenesis via the AMPK-SREBP Transcriptional Pathway.
Submit a Reference

REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 419