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Caspase 7 antibody [Mch3 1-1-11]

Anti-Caspase 7 antibody [Mch3 1-1-11] used in Western Blot (WB). GTX30242
Anti-Caspase 7 antibody [Mch3 1-1-11] used in Western Blot (WB). GTX30242

Cat. No. GTX30242

Reference 1

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 Mch3 1-1-11

Isotype

 IgG1

Application

 WB

Reactivity

 Human, Mouse, Rat
Package
100 μl ($419)
See all Caspase 7 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500 - 1:1000
Not tested in other applications.

Calculated MW

34 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

Ascites

Preservative

0.1% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Full-length recombinant human Caspase 7 [UniProt# P55210]

Purification

Unpurified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

caspase 7 , CASP-7 , CMH-1 , ICE-LAP3 , LICE2 , MCH3

Cellular Localization

Cytoplasm

Background

This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. The precursor of this caspase is cleaved by caspase 3 and 10. It is activated upon cell death stimuli and induces apoptosis. Alternative splicing results in four transcript variants, encoding three distinct isoforms. [provided by RefSeq]

Database

Research Area

DATA IMAGES

Anti-Caspase 7 antibody [Mch3 1-1-11] used in Western Blot (WB). GTX30242

GTX30242 WB Image

WB analysis of HeLa cell lysate using GTX30242 Caspase 7 antibody[Mch3 1-1-11].

Anti-Caspase 7 antibody [Mch3 1-1-11] used in Western Blot (WB). GTX30242

GTX30242 WB Image

WB analysis of HeLa cell lysate using GTX30242 Caspase 7 antibody[Mch3 1-1-11].

REFERENCE

Clone Reference

Blanc-Brude OP et al. Clin Cancer Res 2003; 9 (7):2683-92 Therapeutic targeting of the survivin pathway in cancer: initiation of mitochondrial apoptosis and suppression of tumor-associated angiogenesis.
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REVIEW

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SDS
Sodium Azide.pdf
Package List Price ($)
$ 419