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Caspase 7 (cleaved Asp198) antibody

Anti-Caspase 7 (cleaved Asp198) antibody used in Western Blot (WB). GTX86925
Anti-Caspase 7 (cleaved Asp198) antibody used in IHC (Paraffin sections) (IHC-P). GTX86925

Cat. No. GTX86925

Reference 1

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P

Reactivity

 Human
Package
100 μg ($399)
See all Caspase 7 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500~1:1000
IHC-P 1:50~1:100
Not tested in other applications.

Calculated MW

34 kDa. ( Note )

Product Note

Caspase 7 (cleaved Asp198) antibody detects endogenous levels of fragment of activated Caspase 7 resulting from cleavage adjacent to Asp198.

PROPERTIES

Form

Liquid

Buffer

PBS, 150mM NaCl, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

The antiserum was produced against synthesized peptide derived from human Caspase 7 (180-229).

Purification

Purified by antigen-affinity chromatography
From serum

Conjugation

Unconjugated

RRID

AB_10724148

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

CASP7 , CMH1 , ICELAP3 , LICE2 , MCH3 , caspase 7 , Caspase 7

Cellular Localization

Cytoplasm

Background

This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. The precursor of the encoded protein is cleaved by caspase 3 and 10, is activated upon cell death stimuli and induces apoptosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, May 2012]

Database

Research Area

DATA IMAGES

Anti-Caspase 7 (cleaved Asp198) antibody used in Western Blot (WB). GTX86925

GTX86925 WB Image

WB analysis of 293 cell lysates using GTX86925 Caspase 7 (cleaved Asp198) antibody.

Anti-Caspase 7 (cleaved Asp198) antibody used in IHC (Paraffin sections) (IHC-P). GTX86925

GTX86925 IHC-P Image

IHC-P analysis of human lung carcinoma tissue using GTX86925 Caspase 7 (cleaved Asp198) antibody. The picture on the right is blocked with the synthesized peptide.

REFERENCE

Application Reference

Wang YY et al. ACS Omega 2020; 5 (12) : 7018-7024 Orabase-Formulated Benzalkonium Chloride Effectively Suppressed Oral Potentially Malignant Disorder In Vitro and In Vivo.
Application : WB
Reactivity : Human
Submit a Reference

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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399