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Caspase-8 Inhibitor, Z-IE(OMe)TD(OMe)-FMK

Cat No. GTX47946

Package
20 μl ($199)
PRODUCT

Summary

Cell permeable peptide inhibitor for Caspase 8

APPLICATION

Calculated MW

654.7 Da kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

In DMSO (10 mM)

Storage

Store at -20ºC. Protect from light and moisture.

Concentration

10 mM (Please refer to the vial label for the specific concentration.)

Purity

>99% by HPLC

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

Inhibitor of Caspase 8 , Inhibitor of Caspase8 , Caspase8 Inhibitor (fluoromethylketone) , ZIETDFMK , Z-IETD-FMK , Caspase8 , FLICE Inhibitor , Caspase-8 Inhibitor (fluoromethylketone) , Caspase inhibitor , Z IETD FMK

Background

A synthetic peptide that irreversibly inhibits FLICE and related protease/caspase activity and blocks apoptosis. IETD is the specific recognition sequence found in CPP32 proenzyme. The inhibitor is designed as a methyl ester to facilitate cell permeability. (CAUTION: If the intended use is on purified or recombinant enzymes, esterase should be added to generate free carboxyl groups.)

REFERENCE

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REVIEW

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Package List Price ($)
$ 199